result,correctscules,horedof themal.Reading frame shin by deletioninto the DNA sequence has a large scadamaging effect a delenion may also cause aframe shift Again the result is usually apolypeptide chain of doubtful biological activityNOTE could also lead to nonsensePartial reading frame shiftBoth an insertion and a deletion of bases within agene can cause a frame shift effect where eachcodon no longer has the correct triplet of threebases. In this example, three codons have beenaffected, along with the amino acids they code for.The error is limited to the codons including andbetween the insertion and deletion. There is nobiological activity if the amino acids altered areimportant to the functioning of the resulting protein.1. Explain what is meant by a reading frame shift:DNAMARINAAminaacidsUuuunganggu555555 ⠀⠀⠀⠀BUDURGARAPheTyrLarge scale frame shift resulting in acompletely new sequence of aminoacids. The resulting protein is unlikelyto have any biological activityMutation: Insertion of CTEG0000LysMutation: Deletion of CAwww.g¤¤¤Â¤¤¤...ANANANAMUNDUAGBADABAPhe Val ArgAltered chain which may or may not produce a protein with biological activityLys3. Explain why biological activity of a protein might be affected by a reading frame shift:Val Leu2. Not all gene mutations have the same effect on the organism, some are more disruptive than others.(a) Identify which type of gene mutations are the most damaging to an organism:(b) Explain why they are the most disruptiveMWktwewwGenes & Chromosomes

Answered: 1. Explain what is meant by a reading…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Related questions

Question

result,
correct
scules,
hored
of the
mal.
Reading frame shin by deletion
into the DNA sequence has a large sca
damaging effect a delenion may also cause a
frame shift Again the result is usually a
polypeptide chain of doubtful biological activity
NOTE could also lead to nonsense
Partial reading frame shift
Both an insertion and a deletion of bases within a
gene can cause a frame shift effect where each
codon no longer has the correct triplet of three
bases. In this example, three codons have been
affected, along with the amino acids they code for.
The error is limited to the codons including and
between the insertion and deletion. There is no
biological activity if the amino acids altered are
important to the functioning of the resulting protein.
1. Explain what is meant by a reading frame shift:
DNA
MARINA
Amina
acids
Uuuunganggu
555555 ⠀⠀⠀⠀
BUDURGARA
Phe
Tyr
Large scale frame shift resulting in a
completely new sequence of amino
acids. The resulting protein is unlikely
to have any biological activity
Mutation: Insertion of C
TEG
0000
Lys
Mutation: Deletion of C
A
www.g¤¤¤Â¤¤¤...
ANANANA
MUNDUAGBADABA
Phe Val Arg
Altered chain which may or may not produce a protein with biological activity
Lys
3. Explain why biological activity of a protein might be affected by a reading frame shift:
Val Leu
2. Not all gene mutations have the same effect on the organism, some are more disruptive than others.
(a) Identify which type of gene mutations are the most damaging to an organism:
(b) Explain why they are the most disruptive
M
Wk
twe
ww
Genes & Chromosomes

Expert Solution

Step 1

Codons consist of three nucleotide bases which are encoded for specific amino acids which ultimately results in production of proteins. The way or process in which genetic information is translated into amino acids is basically reading the frame.

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