1. In humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h. This is a sex-linked trait found on the X chromosome. A woman with normal blood clotting has four children: a normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is the genotype for each member of the family?
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- 1. A woman who is heterozygous for hemophilia marries a man with hemophilia. What are the genotypes and phenotypes of the children? a) What is the genotypic ratio of the above cross (Write number next to genotype)? ___________________________________________________________________ b) What is the phenotypic ratio of the above cross? (Write number next to phenotype)? ___________________________________________________________________4. Marfan syndrome is a genetic trait caused by in a dominant allele. The trait causes a weakening of the aorta that can be fatal. A teenager whose mother has the syndrome (but whose maternal grandfather was not affected), and whose father was unaffected, is concerend that she may have the trait. a. What is the phenotype of each of her parents? Genotype? b. What is the chance that the teenager has Marfan syndrome?1. A mother with blood type A has a child with blood type O, What is the mother's genotype? 2. A mother with blood type B has a child with blood type O. What are the possible genotype of the father?
- 1. A mother with blood type A has a child with blood type O, and she claims that Mister X is the father. Mister X denies that he could possibly be the father, because he has blood type B. If you were the judge presiding over this case, which of the following arguments would you find most convincing? a. Mr. X could be the father if his blood genotype is IBIB, and the mother’s blood genotype is IAIA b. Mr. X cannot be the father because a child with blood type O cannot have a parent with blood type B c. Mr. X could be the father if his blood genotype is IBi, and the mother’s blood genotype is IAi d. Mr. X cannot be the father because a parent with blood type B cannot have a child with blood type O e. Mr. X cannot be the father because the human ABO blood types are sex-linked traits 2. A monohybrid cross between two pea plants producing yellow peas, resulting in an F1 phenotypic ratio of 3:1 (three yellow pea plants to one green pea plant) indicates what about the parental pea plants?…3. Hemophilia is a sex linked trait that does not allow for blood clotting normally. It is a recessive genetic defect. In the royal family, the mother of the Prince is a carrier for hemophilia. (XHXh) while the father is normal. ( XHY) . What is the genotype of the Prince if he carries the bleeder’s disease? What is the probability that all the female princesses are normal? Use the Punnett square to show your solution.1. An albino man whose parents are both normal marries a woman one of whose parents is normal and the other albino. She has an albino sister. The couple has a normal son. a. Is albinism a dominant or a recessive trait? Explain your answer. b. Give the genotypes of all the persons involved. c.The couple plans to have more kids. What is the probability of their second child being normal?
- 2. The common grandfather of two first cousins has hereditary hemochromatosis, a recessive condition causing an abnormal buildup of iron in the body. Neither ofthe cousins has the disease nor do any of their relatives.a. If the first cousins had a child, what is the chancethat the child would have hemochromatosis?Assume that the unrelated, unaffected parents ofthe cousins are not carriers.b. How would your calculation change if you knewthat 1 out of every 10 unaffected people in the population (including the unrelated parents of thesecousins) was a carrier for hemochromatosis?9. The factors for normal hemoglobin (S) and sickle-cell hemoglobin (s) are considered codominants: heterozygous individuals have some normal red blood cells and some sickle cells but are not considered to have the disease. A heterozygote is said to have the sickle-cell trait but not the disease. A. What is the genotype of a man with the sickle-cell trait? B. If normal man marries a heterozygous woman, what do you expect for the genotypes and phenotypes of their children? C. If 2 heterozygous people marry and have 3 children who don’t have the disease, what is the chance that their fourth child will have the disease? D. Assume that medical science finds a treatment for sickle-cell anemia so that people with the disease can live out a normal life span but their genes are not changed. If 2 people are saved from the effects of the disease, marry, and have children, what would you expect for the genotypes and phenotypes of their children? Would the children…1) Suppose thatt everyone in your family (bloodline) has attached earlobes. Do you know with certainty what your gentype is? a) Your spouse also has attached earlobes, but both your children have unattached earlobes. What is your genotype, and what is your spouse's genotype?
- 1. How can I explain why a woman had a son with normal vision and normal blood clotting. If she had four sons, and two are colorblind but have normal blood clotting and two have hemophilia but normal color vision. 2, What is the probable genotype of the woman?1. Two people with wavy hair have a straight-haired child. Wavy hair is a dominant. What are the genotypes of the parents? What is the possibility that their next child will have wavy hair? Show the genotype and phenotype ratios that result from the above cross. Show the Punnett square.1. Suppose you identify a new gene in mice. One of its alleles specifies white fur, another specifies brown. You want to see if these alleles are inherited in a Mendelian pattern, or with incomplete dominance. What crosses would give you the answer? Explain. 2. Cystic Fibrosis (CF) is an example of a complex genetic disorder caused by a single mutation. Read section 13.1 Menacing Mucus in your text, and explain the cause and symptoms of CF and justify it as an example of pleiotropy.