10) Which of the following statements is/are TRUE about oxidative phosphorylation? 1. Electron transport provides energy to pump protons into the mitochondrial intermembrane space. ZAn electrochemical gradient is formed across the inner mitochondrial membrane. Electrons form an ionic gradient across the inner mitochondríal membrarie: Complexes I, II, ImI, and IV actively transport protons into the mitochondrial intermembrane space during electron transport. A) 1,2, and 4 B) 1 and 2 )2 and 4 D) 2,3, and 4 E) Trick Question! All of the above statements about oxidative phosphorylation are correct
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Please explain why D)[2,3,&4]is wrong answer and give me the correct answer
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- 1 a) What is meant by the ATP currency exchange ratio? Why does the oxidation of mitochondrial FADH2 generate one less ATP than oxidation of mitochondrial NADH? b) If 12 H+ are moved across the inner mitochondrial membrane by NADH oxidation, and each ATP synthesized requires 3 H+ to move through ATP synthase, why are only 3 ATP molecules produced by oxidation of each NADH?Which of the following statements is NOT true about the electron transport chain (ETC) and oxidative phosphorylation? A. Oxidative phosphorylation requires the enzyme complexes to be soluble in the mitochondrial matrix. B. If the proton gradient is too high, electrons will not move through the ETC. C. The movement of electrons down the ETC only happens if protons are pumped out of the mitochondrial matrix. D. Oxidative phosphorylation requires the mitochondrial intermembrane space to be more positively charged than the matrix. E. The free energy of the proton gradient can be used to create high energy bonds.Which of the following statements is true? A. The NADH dehydrogenase complex can pump more protons than can the cytochrome b-c1 complex. B. The pH in the mitochondrial matrix is higher than the pH in the intermembrane space. C. The proton concentration gradient and the membrane potential across the inner mitochondrial membrane tend to work against each other in driving protons from the intermembrane space into the matrix. D. The difference in proton concentration across the inner mitochondrial membrane has a much larger effect than the membrane potential on the total proton-motive force.
- When the antibiotic X is added to actively respiring mitochondria, several things happen: the yield of ATP decreases, the rate of O2 consumption increases, heat is released, and the pH gradient across the inner mitochondrial membrane increases. Does X act as an uncoupler or an inhibitor of oxidative phosphorylation? Explain the experimental observations in terms of the antibiotic’s ability to transfer K+ ions across the inner mitochondrial membrane.Which of the following statements is NOT true about the electron transport chain (ETC) and oxidative phosphorylation? (Only one answer applies) A. Oxidative phosphorylation requires the enzyme complexes to be soluble in the mitochondrial matrix. B. If the proton gradient is too high, electrons will not move through the ETC. C. The movement of electrons down the ETC only happens if protons are pumped out of the mitochondrial matrix. D. Oxidative phosphorylation requires the mitochondrial intermembrane space to be more positively charged than the matrix. E. The free energy of the proton gradient can be used to create high energy bonds.Where is ATP produced by oxidative phosphorylation? (where is it located immediately after the moment of synthesis) Group of answer choices the mitochondrial matrix the cytoplasm the intermembrane space the inner mitochondrial membrane Which of the following most readily donates electrons? (strongest reducing agent) Group of answer choices NADH NAD+ Ubiquinone lactate Protons first enter ATP synthase through which subunit? Group of answer choices β c γ a
- Fill in the bold using the table. Because the inner mitochondrial membrane is impermeable to L, when there is an excess of mitochondrial L, it converts to M using a TCA condensation reaction, M crosses to the cytosol using a designated transport system. In the cytosol, M reconverts to L and oxaloacetate. Oxaloacetate is subsequently converted to malate with simultaneous production of N, a prerequisite cofactor for the glycolysis pathway. This reaction is then followed by conversion of N to pyruvate which produces O, a prerequisite cofactor for the fatty acid synthesis pathway. L M N O A. ATP pyruvate malate NADPH B. ATP citrate ATP NAD+ C. acetyl CoA pyruvate NAD+ NADH D. acetyl CoA citrate NAD+ NADPH E. glucose pyruvate malate NADP+What is the major route for protons moving from the inter membrane space back into the mitochondrial matrix during oxidative phosphorylation? 1. Protons carried across the membrane by a molecule of dinitrophenol 2. Protons are transported along with ADP by the ATP/ADP translocase.3. Protons enter the half channel in subunit a facing the inter membrane space and exit via the half channel facing the mitochondrial matrix. Choose 1 correct answer explain? Give typing answer with explanation and conclusionThe inner mitochondrial membrane exhibits all of the fundamental characteristics of a typical cell membrane, but it also has several unique characteristics that are closely associated with its role in oxidative phosphorylation. What are these unique characteristics? How does each contribute to the function of the inner membrane?
- 5. a) The cell creates molecules of NADH and FADH2to use in the electron transport chain as they are electron carrier molecules. The electron transfers from these moleculesdrives the movement of what molecule across the mitochondrial membrane?b) What is chemiosmosis?c) How does the cell use chemiosmosis to drive overcome the thermodynamic barrier of bringing phosphates close togehter to create ATP?d) What steps of oxidative phosphorylation are in the cytosol and which are in the mitochondria?e) Cellular respiration can be controlled at the post-translational level. What does this mean, using GLUT as an example? Why is post-translational control of GLUT evolutionarilyadaptive over transcriptional control?f) How does establishment of equillibria of various molecules control metabolic reactions? What are three ways high ATP in the cell control cellular respiration?g) Why are the enzymes controlling the initial steps of various biochemical pathways are targeted by allosteric control?In oxidative phosphorylation.... 1. Succinate contributes 2e- to Complex II and 2H+ to the mitochondrial proton gradient. 2. NADH in the matrix passes 2 e- to coenzyme Q via Complex I. 3. Complexes I, II, III, and IV each contribute to the matrix proton gradient. 4. O2 stabilizes the catalytically active conformation of Complex V. 5. Reversible protonation of c subunits leads to rotation of the Complex V gamma subunit. 6. Each β subunit can bind ATP tightly under the right conditions. 7. For every 3 protons that pass across the inner mitochondrial membrane, 1 ATP is produced. Choose all options that are true.Given that malonate inhibits succinate dehydrogenase which of the following statements is TRUE? a. FADH2 results in only 4 H+ being pumped out of the mitochondrial matrix. b. All electron transport is inhibited. c. Transfer of electrons from NADH to Coenzyme Q (ubiquinone) is inhibited. d. Transfer of electrons from FADH2 to Coenzyme Q (ubiquinone) is inhibited. e. NADH results in only 4 H+ being pumped out of the mitochondrial matrix. Clear my choice