Oxidative Phosphorylation (Ch. 19) 1. The NADH dehydrogenase complex of the mitochondrial respiratory chain promotes the following series of oxidation-reduction reactions, in which Fe* and Fe2* represent the iron in iron-sulfur centers, Q is ubiquinone, QH2 is ubiquinol, and E is the enzyme: (1) NADH + H* + E-FMN → NAD* + E-FMNH2 (2) E-FMNH2 + 2Fe³+ (3) 2FE2+ + 2H* + Q· → E-FMN + 2Fe²+ + 2H+ 2Fe3+ + QH2 Sum: NADH + H* + Q–→ NAD* + QH2 For each of the three reactions catalyzed by the NADH dehydrogenase complex, identify (a) the electron donor, (b) the electron acceptor, (c) the conjugate redox pair, (d) the reducing agent, and (e) the oxidizing agent.

Biochemistry
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ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter20: Electron Transport And Oxidative Phosphorylation
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Oxidative Phosphorylation (Ch. 19)
1. The NADH dehydrogenase complex of the mitochondrial respiratory chain promotes the
following series of oxidation-reduction reactions, in which Fe* and Fe2* represent the iron in
iron-sulfur centers, Q is ubiquinone, QH2 is ubiquinol, and E is the enzyme:
(1) NADH + H* + E-FMN → NAD* + E-FMNH2
(2) E-FMNH2 + 2Fe³+
(3) 2FE2+ + 2H* + Q·
→ E-FMN + 2Fe²+ + 2H+
2Fe3+ + QH2
Sum: NADH + H* + Q–→ NAD* + QH2
For each of the three reactions catalyzed by the NADH dehydrogenase complex, identify
(a) the electron donor, (b) the electron acceptor, (c) the conjugate redox pair, (d) the reducing
agent, and (e) the oxidizing agent.
Transcribed Image Text:Oxidative Phosphorylation (Ch. 19) 1. The NADH dehydrogenase complex of the mitochondrial respiratory chain promotes the following series of oxidation-reduction reactions, in which Fe* and Fe2* represent the iron in iron-sulfur centers, Q is ubiquinone, QH2 is ubiquinol, and E is the enzyme: (1) NADH + H* + E-FMN → NAD* + E-FMNH2 (2) E-FMNH2 + 2Fe³+ (3) 2FE2+ + 2H* + Q· → E-FMN + 2Fe²+ + 2H+ 2Fe3+ + QH2 Sum: NADH + H* + Q–→ NAD* + QH2 For each of the three reactions catalyzed by the NADH dehydrogenase complex, identify (a) the electron donor, (b) the electron acceptor, (c) the conjugate redox pair, (d) the reducing agent, and (e) the oxidizing agent.
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