10. Patient was admitted to the hospital with complaints on malnutrition, light- colored feces, urinc colored as «brown ale»; it was revealed icteric discolor of skin and sclera. Due to examination and laboratory serum tests, the doctor diagnosed viral hepatitis. Why blood test is revealed the considerable increase of transaminase activity (ALT and AST) in this patient? For the answer: a) explain the reason for mentioned enzymes increased activity in the blood; b) specify, what enzyme activity is increased in the largest degree in this pathology and why;
10. Patient was admitted to the hospital with complaints on malnutrition, light- colored feces, urinc colored as «brown ale»; it was revealed icteric discolor of skin and sclera. Due to examination and laboratory serum tests, the doctor diagnosed viral hepatitis. Why blood test is revealed the considerable increase of transaminase activity (ALT and AST) in this patient? For the answer: a) explain the reason for mentioned enzymes increased activity in the blood; b) specify, what enzyme activity is increased in the largest degree in this pathology and why;
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 2.1P
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Transcribed Image Text:10. Patient was admitted to the hospital with complaints on malnutrition, light-
colored feces, urine colored as «brown ale»; it was revealed icteric discolor of
skin and sclera. Due to examination and laboratory serum tests, the doctor
diagnoscd viral hepatitis. Why blood test is revealed the considerable increase
of transaminase activity (ALT and AST) in this patient? For the answer:
a) explain the reason for mentioned enzymes increascd activity in the blood;
b) specify, what enzyme activity is increased in the largest degree in this
pathology and why;
8.3. Ammonia Detoxification. Urea Cycle. Urea Cycle Disorders, Hyperammonemia
413
c) draw the graph indicating the change of these enzymes activity in this disorder;
d) write down reactions catalyzed by these enzymes, give full names of direct
and reversible reactions, specify coenzyme;
e) point out thc Ritz ratio in this disorder.
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