14. DNA methyltransferase, an enzyme that methylates DNA, ----. a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b. , is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. , is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because ----. a. the cell has just emerged from the quiescent GO phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the G1 phase

14. DNA methyltransferase, an enzyme that methylates DNA, ----. a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b. , is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. , is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because ----. a. the cell has just emerged from the quiescent GO phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the G1 phase

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter15: Genes And Proteins

Section: Chapter Questions

Problem 12RQ: How do enhancers and promoters differ? Enhancers bind transcription factors to silence gene...

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