2. a) Below are the compounds (A) Codeine, (B) Methadone and (C) morphine. What would be the predicted HPLC elution order using a C-18 reverse phase column, 5 µm particles and 50% acetonitrile/H2O mobile phase? Explain Meo HO -Me HO" HO A B b) Rank the following solvent in terms of elutropic strength for Normal Phase chromatography (Ethyl Acetate, Acetonitrile, H2O and Pentane.) (

2. a) Below are the compounds (A) Codeine, (B) Methadone and (C) morphine. What would be the predicted HPLC elution order using a C-18 reverse phase column, 5 µm particles and 50% acetonitrile/H2O mobile phase? Explain Meo HO -Me HO" HO A B b) Rank the following solvent in terms of elutropic strength for Normal Phase chromatography (Ethyl Acetate, Acetonitrile, H2O and Pentane.) (

Appl Of Ms Excel In Analytical Chemistry

2nd Edition

ISBN:9781285686691

Author:Crouch

Publisher:Crouch

Chapter4: Least-squares And Calibration Methods

Section: Chapter Questions

Problem 3P

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