2. A pharmacologist discovers a new fungal metabolite with unusual antimicrobial properties. It naturally concentrates in the endosomes, lysosomes, and phagolysosomes of cells and directly kills microorganisms (eg. Mycobacterium tuberculosis) that are normally resistant to degradation in the phagolysosomes. It has the undesirable effect of raising the pH within phagolysosomes. Which of the following processes will be primarily affected? A) Class I MHC molecule peptide loading o B) Class II MHC molecule peptide loading C) B-Microglobulin surface expression D) Peptide binding to TCRaß E) Peptide binding to TCRYO

2. A pharmacologist discovers a new fungal metabolite with unusual antimicrobial properties. It naturally concentrates in the endosomes, lysosomes, and phagolysosomes of cells and directly kills microorganisms (eg. Mycobacterium tuberculosis) that are normally resistant to degradation in the phagolysosomes. It has the undesirable effect of raising the pH within phagolysosomes. Which of the following processes will be primarily affected? A) Class I MHC molecule peptide loading o B) Class II MHC molecule peptide loading C) B-Microglobulin surface expression D) Peptide binding to TCRaß E) Peptide binding to TCRYO

Biology: The Unity and Diversity of Life (MindTap Course List)

14th Edition

ISBN:9781305073951

Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Chapter20: Viruses, Bacteria, And Archaea

Section: Chapter Questions

Problem 1CT: If a cut or scrape becomes infected, Staphylococcus aureus is probably the culprit (right). These...

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