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29. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na CI- A) Angiotensin-converting enzyme B) Aquaporin C) 11a-Hydroxylase D) Renin E) Vasopressin receptors Osmolality Specific gravity Osmolality Urine 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) 334 mOsmol/kg H₂O (N=282-295) 1.001 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the referem ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonogra shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following?

29. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na CI- A) Angiotensin-converting enzyme B) Aquaporin C) 11a-Hydroxylase D) Renin E) Vasopressin receptors Osmolality Specific gravity Osmolality Urine 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) 334 mOsmol/kg H₂O (N=282-295) 1.001 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the referem ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonogra shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following?

Ebk:Nutrition & Diet Therapy
Ebk:Nutrition & Diet Therapy
10th Edition
ISBN:9780357391747
Author:DEBRUYNE
Publisher:DEBRUYNE
Chapter23: Protein-, Mineral-, And Fluid-modified Diets For Kidney Diseases
Section: Chapter Questions
Problem 4SC
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29. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na+ CI- A) Angiotensin-converting enzyme B) Aquaporin C) 11a-Hydroxylase D) Renin E) Vasopressin receptors Osmolality Specific gravity Osmolality Urine 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) 334 mOsmol/kg H₂O (N=282-295) 1.001 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the referenc ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonograp shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following?
Transcribed Image Text:29. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na+ CI- A) Angiotensin-converting enzyme B) Aquaporin C) 11a-Hydroxylase D) Renin E) Vasopressin receptors Osmolality Specific gravity Osmolality Urine 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) 334 mOsmol/kg H₂O (N=282-295) 1.001 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the referenc ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonograp shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following?
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