Answered: 36. The ring-opening of cyclic ethers…

36. The ring-opening of cyclic ethers happens through cleavage by suitable nucleophiles. Which among the structures below will be the most susceptible to ring- opening? A. B. C. D.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter11: Ethers, Epoxides, And Sulfides

Section11.4: Preparation Of Ethers

Problem 11.3P: Show how you might use the Williamson ether synthesis to prepare each ether. (a) (b)

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Concept explainers

Organomagnesium compounds

The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.

Hydrolysis Grignard Reactions and Reduction

Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.

Question

Aldehydes undergo nucleophilic addition reactions with potent nucleophiles such as water, alcohol and amino compounds. Which of the following nucleophiles will exhibit the greatest ability to attack the electrophilic carbon in the carbonyl group of ethanal?

Group of answer choices

cyclohexyl alcohol

para-chlorophenol

isoamyl alcohol

ortho-aminophenol

An aromatic ring should satisfy Huckel’s rule, wherein the number of electrons participating in the cyclic conjugation should be equal to 4n + 2. Which of the following cyclic structures does NOT obey Huckel’s rule?

Group of answer choices

Cyclobutadienyl dianion

Tetrahydrofuran ring

Cyclopropene structure

Pyrimidine ring structure

36. The ring-opening of cyclic ethers happens through cleavage by suitable
nucleophiles. Which among the structures below will be the most susceptible to ring-
opening?
A.
B.
C.
D.

Definition Definition Organic compounds with a planar cyclic ring of atoms bonded through alternated single and double bonds. Aromatic organic compounds, also called arenes, are an important class of hydrocarbons under the branch of organic chemistry.

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