4. Muscle cells are full of the actin and myosin proteins. a. Briefly describe the arrangement of the actin and myosin molecules within the cell. How does the interaction between actin and myosin result in shortening of the muscle cell? b. Which molecule provides the energy to break the actin-myosin bond? c. Would the muscle be able to contract if they run out of energy? Explain why. d. What happens to muscles in the case of death? Why do the muscles stay in contracted state and relax only after a certain period of time?

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter8: Muscle Physiology
Section: Chapter Questions
Problem 8RE
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Shirley was assigned to take Mr. Aletha to physical therapy. She helped Mr. Aletha into the wheelchair and took
him down the hallway to the room where he was to receive strengthening exercises for his generalized muscle
weakness. Mr. Aletha told Shirley that he often felt okay at the beginning of his therapy session but became
weaker as the session progressed. Mr. Aletha was in the hospital because of this perplexing problem. One day
Shirley went to Mr. Aletha's room to take him to therapy, but Mr. Aletha told her that the sessions were
canceled: The therapy would not help his condition because he had myasthenia gravis. Shirley had heard about
this disease but did not understand the physiology. She went to her anatomy text and began to read the
chapters on muscle contraction and nerve transmission. Help her answer the following questions so she can put
this puzzling disease in perspective.
Normal
You
Synaptic end bulb,
Axon
Action
potential
Synaptic-
vesicles
Motor neuron
Voltage-gated
Ca channel
89
Synaptic cleft
No Spacing
T-tubule-
Heading 1
Motor end plate
Muscle
fibers
-Neurotransmitter
Neurotransmitter
receptors
W
Heading 2
PrtSc
Titl
Insert
Foc
Transcribed Image Text:E E ALT - Q Search 5 Paragraph Styles Shirley was assigned to take Mr. Aletha to physical therapy. She helped Mr. Aletha into the wheelchair and took him down the hallway to the room where he was to receive strengthening exercises for his generalized muscle weakness. Mr. Aletha told Shirley that he often felt okay at the beginning of his therapy session but became weaker as the session progressed. Mr. Aletha was in the hospital because of this perplexing problem. One day Shirley went to Mr. Aletha's room to take him to therapy, but Mr. Aletha told her that the sessions were canceled: The therapy would not help his condition because he had myasthenia gravis. Shirley had heard about this disease but did not understand the physiology. She went to her anatomy text and began to read the chapters on muscle contraction and nerve transmission. Help her answer the following questions so she can put this puzzling disease in perspective. Normal You Synaptic end bulb, Axon Action potential Synaptic- vesicles Motor neuron Voltage-gated Ca channel 89 Synaptic cleft No Spacing T-tubule- Heading 1 Motor end plate Muscle fibers -Neurotransmitter Neurotransmitter receptors W Heading 2 PrtSc Titl Insert Foc
4
R
F
4. Muscle cells are full of the actin and myosin proteins.
a. Briefly describe the arrangement of the actin and myosin molecules within the cell. How does the interaction
between actin and myosin result in shortening of the muscle cell?
b. Which molecule provides the energy to break the actin-myosin bond?
c. Would the muscle be able to contract if they run out of energy? Explain why.
d. What happens to muscles in the case of death? Why do the muscles stay in contracted state and relax only
after a certain period of time?
5. Myasthenia gravis is an autoimmune disease in which the body's immune cells attack and destroy the
acetylcholine (Ach) receptors in the motor end plates of muscles in the shoulder, neck, and face. When muscle
do not contracts. Muscle atrophy (loss of muscle mass) is caused by not using the muscles enough. Why would
Mr. Aletha experience a progressive weakening even if he tries to do more exercise?
6. Do aerobic (endurance) and resistance exercises produce the same effect on muscles? How do endurance
and anaerobic exercises normally enhance your ability to contract muscles?
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Transcribed Image Text:4 R F 4. Muscle cells are full of the actin and myosin proteins. a. Briefly describe the arrangement of the actin and myosin molecules within the cell. How does the interaction between actin and myosin result in shortening of the muscle cell? b. Which molecule provides the energy to break the actin-myosin bond? c. Would the muscle be able to contract if they run out of energy? Explain why. d. What happens to muscles in the case of death? Why do the muscles stay in contracted state and relax only after a certain period of time? 5. Myasthenia gravis is an autoimmune disease in which the body's immune cells attack and destroy the acetylcholine (Ach) receptors in the motor end plates of muscles in the shoulder, neck, and face. When muscle do not contracts. Muscle atrophy (loss of muscle mass) is caused by not using the muscles enough. Why would Mr. Aletha experience a progressive weakening even if he tries to do more exercise? 6. Do aerobic (endurance) and resistance exercises produce the same effect on muscles? How do endurance and anaerobic exercises normally enhance your ability to contract muscles? ▬ % 5 T Q Search G F6 6 Y H & 7 U J e * 8 DE F10 ( 9 K O ** F11 0 ** P F12 PrtSc Insert 1/
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