Examples of X-linked recessive disorders:• Red-green color-blindness• Hemophilia (fig. 92)• Duchenne muscular dystrophy (DMD)Father hashemophilia XYMother is not a carrierof the hemophilia gene XXFather does notMother is a carrierhave hemophilla XYof the hemophilia gene XX50% chancedaughters will be a carrierof the hemophilia gene XX50% chancesons will havehemophilia XY0% chancesons will have100% chancedaughters will be a carrierof the hemophilia gene XXhemophilia XYDoes not haveKey HemophilaHas HemophiliaCarrier of theKeyDoes not haveHermophiliaCarrier of theHemophilia geneHas HemophiliaHemophilia geneabFig. 92. Inheritance of hemophilia or bleeder's disease (a) when motheris a carrier, and (b) when father has the condition. 4. What mode of inheritance is shown in thepedigree chart on the left? Justify youranswer.5. Construct pedigree charts using the inheritance of hemophilia in figure92 (page 113). This is X-linked inheritance so you are required to labelXX for females and XY for males. The gene responsible for the trait isrepresented by the superscript which should be specified in the legend.

Name: Examples of X-linked recessive disorders:• Red-green color-blindness•
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Description: Examples of X-linked recessive disorders:• Red-green color-blindness• Hemophilia (fig. 92)• Duchenne muscular dystrophy (DMD)Father hashemophilia XYMother is not a carrierof the hemophilia gene XXFather does notMother is a carrierhave hemophilla XYo

Pedigree is a branching representation indicating family members of everi generation . Pedigree…

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4. What mode of inheritance is shown in the pedigree chart on the left? Justify your answer. 5. Construct pedigree charts using the inheritance of hemophilia in figure 92 (page 113). This is X-linked inheritance so you are required to label XX for females and XY for males. The gene responsible for the trait is represented by the superscript which should be specified in the legend.

4. What mode of inheritance is shown in the pedigree chart on the left? Justify your answer. 5. Construct pedigree charts using the inheritance of hemophilia in figure 92 (page 113). This is X-linked inheritance so you are required to label XX for females and XY for males. The gene responsible for the trait is represented by the superscript which should be specified in the legend.

Biology: The Unity and Diversity of Life (MindTap Course List)

15th Edition

ISBN:9781337408332

Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Chapter14: Chromosomes And Human Inheritance

Section: Chapter Questions

Problem 1GP: Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance...

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The following pedigree shows the pattern of inheritance of red green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in red. What is the chance that a son of the third-generation female indicated by the arrow will be color-blind if the father is a normal man? If the father is color-blind?
Individuals affected by a condition known as polydactyly have extra fingers or toes. The following pedigree shows the pattern of inheritance of this trait in one family: From the pedigree, can you tell if polydactyly comes from a dominant or recessive allele? Is the trait sex-linked? As far as you can determine, what is the genotype of each person in the pedigree with respect to the trait?
1. Construct pedigree charts using the inheritance of hemophilia in figure 92. This is X-linked inheritance so you are required to label XX for females and XY for males. The gene responsible for the trait is represented by the superscript which should be specified in the legend.
1-In a pedigree analysis a family shows a possible autosomal recessive inheritance, however karyotype analysis shows a normal chromosomal pattern in all affected, can you suggest a possible explanation for this out come?
4. Marfan syndrome is a genetic trait caused by in a dominant allele. The trait causes a weakening of the aorta that can be fatal. A teenager whose mother has the syndrome (but whose maternal grandfather was not affected), and whose father was unaffected, is concerend that she may have the trait. a. What is the phenotype of each of her parents? Genotype? b. What is the chance that the teenager has Marfan syndrome?
8. Consider the following hypothetical cross: Tall, + tendrils X Short, - tendrils F1: Tall, + tendrils F1’s are backcrossed to recessive parent. 850 progeny produced: Tall, + tendrils 221; Tall, - tendrils 195; short, + tendrils 190, short, - tendrils 194. Explain pattern of inheritance.
1-Gigantism is being traced in a family through a pedigree. Its mode of inheritance is thought to be autosomal recessive. You examine the pedigree and decide that the mode of inheritance is not correct. What is the correct mode of inheritance? 2-Provide 2 pieces of evidence for the mode of inheritance selected for Gigantism. (i.e.- Individual 45 is afflicted and passed it on to all of her offspring, indicating that it is dominant. Or there is a gendered pattern of inheritance seen when Individual 99 passed it on to only his female offspring.)
8. Huntington’s disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. A. What is the genotype of a man who is normal but whose father had Huntington’s disease? B. What is the genotype of a woman who has Huntington’s disease if both of her parents had Huntington’s disease? C. If a man who is heterozygous for Huntington’s disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? D. If a normal man marries a woman who is homozygous for Huntington’s disease, what do you expect for the genotypes and phenotypes of their children?
1. Give the probable mode of Inheritance and justify your answer. 2. Indicate the most probable genotype of each member of the pedigree
1) By convention, the recessive trait will determine the abbreviation used to track crosses if it is a mutant condition, since it stands out in contrast to the rest of the population. For example, if pea pods are typically green in color, a mutant condition might result in yellow pea pods; therefore, the lowercase letter ‘y’ would be used to depict the mutant state, yellow, while uppercase ‘Y’ would depict the wildtype (wt) condition, green. Remember that the mutant condition is not necessarily always recessive. 1 A) . If green is dominant wt (Y) and yellow is a recessive mutant condition (y), depict a Yy father mated with a YY mother in the Punnett. 1B) Considering the dominant allele, what colors are the parents in the cross above? Yy = _____________________ YY = _____________________ 1C) What colors are the offspring in the cross above? 1D) What is the phenotypic ratio of the offspring? 1E) What is the genotypic ratio of the offspring? (Remember, the genotypic ratio is based…
9. Red-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___
4. In the pedigree shown, the trait is most likely caused by what type of inheritance? X-linked dominant autosomal recessive autosomal dominant X-linked recessive