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5 de 21 2.4. Goniometry Measurements Dog Z showed improvement in almost all joints measured except flexion of the shoulder, stifle and extension of the hip (Table 1A). Dog B improved in all measured joints (Table 1B). Dog M demonstrated slight improvement in the pelvic limbs, in extension as well as flexion, with no improvement or a little worsening in the thoracic limbs (Table 1C). Table 1. Goniometric measurements of mobility. (A, B, C) Measurements of flexion and extension according to the anatomical coordinates for shoulder, elbow, carpus, hip, stifle were performed in Dogs Z, B and M successively. A Shoulder B Dog Z Elbow Carpus Hip Stifle Tarsus Int. J. Mol. Sci. 2020, 21, 5129 flexion extension flexion extension flexion extension flexion extension flexion extension Shoulder flexion extension Dog B Elbow flexion extension flexion extension flexion Right Limb Before Treatment. 30 1 1401.7 35 +1.7 175 1 161 220 +3.4 39 ±2.6 1742 201 1701 25+1 1651 After Treatment 40+ 1.7 175 + 2 20+ 1.7 1551 15 1 185 ± 1.7 391 140 + 1.7 10+1 175 1 251 190 + 1 Table 1. Cont. Right Limb Before After Treatment Treatment 481 55±2.6 137.50.8 160 ± 2.6 26 +1 202.6 1431 162 ± 1.5 14+17 16+? Left Limb Before Treatment 25 +1.7 1651 30 + 1 1601.7 16 1 220 +2.6 40+ 1.7 170±2 25 + 1.7 1821 15 + 1 185 + 1.7 Before Treatment 89 ± 1.7 1782 25+ 2 175 +1.7 After Treatment 30+ 1.7 Left Limb 15+17 1761.7 20+2 170 +3.4 14+ 1 1901 40 + 1 157 1 17 + 1.7 1681 15+1 1851 After Treatment 45+2 169±1.3 19 +1.7 163 ± 1.7 16+1 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges. 30-60 160-170 20-40 160-170 20-35 6 of 21

5 de 21 2.4. Goniometry Measurements Dog Z showed improvement in almost all joints measured except flexion of the shoulder, stifle and extension of the hip (Table 1A). Dog B improved in all measured joints (Table 1B). Dog M demonstrated slight improvement in the pelvic limbs, in extension as well as flexion, with no improvement or a little worsening in the thoracic limbs (Table 1C). Table 1. Goniometric measurements of mobility. (A, B, C) Measurements of flexion and extension according to the anatomical coordinates for shoulder, elbow, carpus, hip, stifle were performed in Dogs Z, B and M successively. A Shoulder B Dog Z Elbow Carpus Hip Stifle Tarsus Int. J. Mol. Sci. 2020, 21, 5129 flexion extension flexion extension flexion extension flexion extension flexion extension Shoulder flexion extension Dog B Elbow flexion extension flexion extension flexion Right Limb Before Treatment. 30 1 1401.7 35 +1.7 175 1 161 220 +3.4 39 ±2.6 1742 201 1701 25+1 1651 After Treatment 40+ 1.7 175 + 2 20+ 1.7 1551 15 1 185 ± 1.7 391 140 + 1.7 10+1 175 1 251 190 + 1 Table 1. Cont. Right Limb Before After Treatment Treatment 481 55±2.6 137.50.8 160 ± 2.6 26 +1 202.6 1431 162 ± 1.5 14+17 16+? Left Limb Before Treatment 25 +1.7 1651 30 + 1 1601.7 16 1 220 +2.6 40+ 1.7 170±2 25 + 1.7 1821 15 + 1 185 + 1.7 Before Treatment 89 ± 1.7 1782 25+ 2 175 +1.7 After Treatment 30+ 1.7 Left Limb 15+17 1761.7 20+2 170 +3.4 14+ 1 1901 40 + 1 157 1 17 + 1.7 1681 15+1 1851 After Treatment 45+2 169±1.3 19 +1.7 163 ± 1.7 16+1 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges. 30-60 160-170 20-40 160-170 20-35 6 of 21

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Please read these results and explain them briefly in a way that is understood https://mdpi-res.com/d_attachment/ijms/ijms-21-05129/article_deploy/ijms-21-05129.pdf?version=1595262192
6:01 p. m. Vie 29 sep. 5 de 21 2.4. Goniometry Measurements Dog Z showed improvement in almost all joints measured except flexion of the shoulder, stifle and extension of the hip (Table 1A). Dog B improved in all measured joints (Table 1B). Dog M demonstrated slight improvement in the pelvic limbs, in extension as well as flexion, with no improvement or a little worsening in the thoracic limbs (Table 1C). Table 1. Goniometric measurements of mobility. (A, B, C) Measurements of flexion and extension according to the anatomical coordinates for shoulder, elbow, carpus, hip, stifle were performed in Dogs Z, B and M successively. A Shoulder B Dog Z Elbow Carpus Hip Stifle Tarsus flexion extension flexion extension flexion extension flexion extension Int. J. Mol. Sci. 2020, 21, 5129 Shoulder flexion extension Elbow flexion extension Dog B flexion extension flexion extension flexion mdpi-res.com Right Limb Before Treatment 30 + 1 140 ± 1.7 35±1.7 175 + 1 16+1 220 ± 3.4 39±2.6 174 + 2 20+1 170 + 1 25+1 165 +1 Before Treatment 48 +1 137.5 +0.8 26±1 143 ± 1 14 + 1.7 After Treatment 40 + 1.7 175 + 2 20 + 1.7 155 ± 1 151 185 1.7 39 +1 140 + 1.7 10 + 1 175 +1 25+1 1901 Table 1. Cont. Right Limb After Treatment 55 +2.6 160±2.6 20 +2.6 162 ± 1.5 162 Left Limb Before Treatment 25 +1.7 1651 30 + 1 160 ± 1.7 16+1 220 +2.6 40+ 1.7 170 ± 2 25 +1.7 182 +1 151 185±1.7 After Treatment 30+ 1.7 176 ± 1.7 20+2 170 ± 3.4 141 1901 40+1 157 +1 17 + 1.7 1681 15 + 1 1851 Left Limb Before Treatment 89±1.7 1782 25+2 175 +1.7 151.7 After Treatment 45 + 2 169 ± 1.3 19 + 1.7 163 ± 1.7 16 1 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges 30-60 160-170 20-40 160-170 20-35 6 of 21 17%
Transcribed Image Text:6:01 p. m. Vie 29 sep. 5 de 21 2.4. Goniometry Measurements Dog Z showed improvement in almost all joints measured except flexion of the shoulder, stifle and extension of the hip (Table 1A). Dog B improved in all measured joints (Table 1B). Dog M demonstrated slight improvement in the pelvic limbs, in extension as well as flexion, with no improvement or a little worsening in the thoracic limbs (Table 1C). Table 1. Goniometric measurements of mobility. (A, B, C) Measurements of flexion and extension according to the anatomical coordinates for shoulder, elbow, carpus, hip, stifle were performed in Dogs Z, B and M successively. A Shoulder B Dog Z Elbow Carpus Hip Stifle Tarsus flexion extension flexion extension flexion extension flexion extension Int. J. Mol. Sci. 2020, 21, 5129 Shoulder flexion extension Elbow flexion extension Dog B flexion extension flexion extension flexion mdpi-res.com Right Limb Before Treatment 30 + 1 140 ± 1.7 35±1.7 175 + 1 16+1 220 ± 3.4 39±2.6 174 + 2 20+1 170 + 1 25+1 165 +1 Before Treatment 48 +1 137.5 +0.8 26±1 143 ± 1 14 + 1.7 After Treatment 40 + 1.7 175 + 2 20 + 1.7 155 ± 1 151 185 1.7 39 +1 140 + 1.7 10 + 1 175 +1 25+1 1901 Table 1. Cont. Right Limb After Treatment 55 +2.6 160±2.6 20 +2.6 162 ± 1.5 162 Left Limb Before Treatment 25 +1.7 1651 30 + 1 160 ± 1.7 16+1 220 +2.6 40+ 1.7 170 ± 2 25 +1.7 182 +1 151 185±1.7 After Treatment 30+ 1.7 176 ± 1.7 20+2 170 ± 3.4 141 1901 40+1 157 +1 17 + 1.7 1681 15 + 1 1851 Left Limb Before Treatment 89±1.7 1782 25+2 175 +1.7 151.7 After Treatment 45 + 2 169 ± 1.3 19 + 1.7 163 ± 1.7 16 1 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges 30-60 160-170 20-40 160-170 20-35 6 of 21 17%
6:01 p. m. Vie 29 sep. Int. J. Mol. Sci. 2020, 21, 5129 B Shoulder с Dog B Elbow Carpus Hip Stifle Tarsus Shoulder Elbow Hip Dog M Carpus Stifle flexion extension Tarsus flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension Before Treatment 481 137.5 ± 0.8 26±1 143 1 14 + 1.7 163 1 10+2 145 + 1 22 ±2.6 130 +1.7 30+2 Right Limb 145 1.7 mdpi-res.com Table 1. Cont. Before Treatment 45+1 1852 35+2 218 ± 1.7 19 +2 168 +2 13+1 1871 19+2 1841 35 ± 1.7 185 +1 After Treatment 55 +2.6 160 ± 2.6 20±2.6 162 ± 1.5 16 +2 190 ± 2 10+ 1.7 129 +2 25+ 2 145 + 1.7 392 153 ± 2 Right Limb After Treatment 352 140 + 1.7 30+ 1.7 184 ± 1.7 20+2 1241.7 10 + 1 180 1.7 22 +1 170 + 2 40+ 1.7 185 ± 1.7 Left Limb Before Treatment 89±1.7 178 +2 25 + 2 175 +1.7 15 +1.7 175 + 2 381 96 +2 40+2 135 + 1.7 20±2.6 1451 After Treatment 45+2 169 ± 1.3 19 +1.7 163 ± 1.7 16+1 180 ± 2 321 145±2.6 45 +1.7 155 +3 281 1681.7 Left Limb Before Treatment 49 ± 1.7 200 + 2 28 ± 1 1832 19 +2 210 ± 2 8+1 169 +1 10+ 1.7 175 +2.6 25 +1.7 173 +2 After Treatment 35+2 170±2.6 30+1 210 + 2 19 + 1 235 +2 20+2 180 ± 2.6 20+1 130 +2 30+ 1.7 190 +1.7 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 6 of 21 17%
Transcribed Image Text:6:01 p. m. Vie 29 sep. Int. J. Mol. Sci. 2020, 21, 5129 B Shoulder с Dog B Elbow Carpus Hip Stifle Tarsus Shoulder Elbow Hip Dog M Carpus Stifle flexion extension Tarsus flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension flexion extension Before Treatment 481 137.5 ± 0.8 26±1 143 1 14 + 1.7 163 1 10+2 145 + 1 22 ±2.6 130 +1.7 30+2 Right Limb 145 1.7 mdpi-res.com Table 1. Cont. Before Treatment 45+1 1852 35+2 218 ± 1.7 19 +2 168 +2 13+1 1871 19+2 1841 35 ± 1.7 185 +1 After Treatment 55 +2.6 160 ± 2.6 20±2.6 162 ± 1.5 16 +2 190 ± 2 10+ 1.7 129 +2 25+ 2 145 + 1.7 392 153 ± 2 Right Limb After Treatment 352 140 + 1.7 30+ 1.7 184 ± 1.7 20+2 1241.7 10 + 1 180 1.7 22 +1 170 + 2 40+ 1.7 185 ± 1.7 Left Limb Before Treatment 89±1.7 178 +2 25 + 2 175 +1.7 15 +1.7 175 + 2 381 96 +2 40+2 135 + 1.7 20±2.6 1451 After Treatment 45+2 169 ± 1.3 19 +1.7 163 ± 1.7 16+1 180 ± 2 321 145±2.6 45 +1.7 155 +3 281 1681.7 Left Limb Before Treatment 49 ± 1.7 200 + 2 28 ± 1 1832 19 +2 210 ± 2 8+1 169 +1 10+ 1.7 175 +2.6 25 +1.7 173 +2 After Treatment 35+2 170±2.6 30+1 210 + 2 19 + 1 235 +2 20+2 180 ± 2.6 20+1 130 +2 30+ 1.7 190 +1.7 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 Normal Ranges 30-60 160-170 20-40 160-170 20-35 190-200 55 160-165 45 160-170 40 170 6 of 21 17%
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