Determine the expiration date of a drug product with the initial drug concentration of 50 mg/tablet using the following accelerated stability testing data: Accelerated Stability Testing Data Temp (oC) Rate Constant (l/min) 70 1.73E-05 80 3.38E-05 90 6.45E-05 Reaction Kinetics- Accelerated Stability Testing Temp (oC) 70 8.0 Temp (K) Rate Constant (l/min) 1/T 1.73E-05 3.38E-05 1/T (1/K) log k In k log k
Determine the expiration date of a drug product with the initial drug concentration of 50 mg/tablet using the following accelerated stability testing data: Accelerated Stability Testing Data Temp (oC) Rate Constant (l/min) 70 1.73E-05 80 3.38E-05 90 6.45E-05 Reaction Kinetics- Accelerated Stability Testing Temp (oC) 70 8.0 Temp (K) Rate Constant (l/min) 1/T 1.73E-05 3.38E-05 1/T (1/K) log k In k log k
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Transcribed Image Text:Accelerated Stability Testing Data
Determine the expiration
date of a drug product
with the initial drug
concentration of 50
mg/tablet using the
following accelerated
stability testing data:
log
Temp
Rate Constant (1/min)
1/T
(oC)
70
1.73E-05
80
3.38E-05
90
6.45E-05
Reaction Kinetics - Accelerated Stability Testing
log
In k
Rate Constant
Temp
(oC)
Temp
(к)
(1/min)
(1/K)
k
70
1.73E-05
80
3.38E-05
90
6.45E-05
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