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7 I myosin heads firmly bound to actin 8. | threshold is reached and muscle action potential is generated sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 6. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasn (End of Excitation Steps) 10 11 E activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and repeat the cycle 12 13 I new ATP molecule binds to open ATP binding site of myosin ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 calcium binds troponin on sarcomeres of myofibril I muscle action potential travels down sarcolemma and t-tubules 16 I tropomyosin slides out of position, off myosin binding sites on actin 17 I myosin quickly breaks phosphate bond of ATP 18 motor neuron action potential travels down axon, stimulating ACh release from terminals 19

7 I myosin heads firmly bound to actin 8. | threshold is reached and muscle action potential is generated sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 6. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasn (End of Excitation Steps) 10 11 E activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and repeat the cycle 12 13 I new ATP molecule binds to open ATP binding site of myosin ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 calcium binds troponin on sarcomeres of myofibril I muscle action potential travels down sarcolemma and t-tubules 16 I tropomyosin slides out of position, off myosin binding sites on actin 17 I myosin quickly breaks phosphate bond of ATP 18 motor neuron action potential travels down axon, stimulating ACh release from terminals 19

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Arrange the steps of muscle excitation and contraction in the correct order.
myosin heads firmly bound to actin 8. i threshold is reached and muscle action potential is generated sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 9. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasm (End of Excitation Steps) 10 11 | activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and repeat the cycle 12 | new ATP molecule binds to open ATP binding site of myosin 13 ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 | calcium binds troponin on sarcomeres of myofibril I muscle action potential travels down sarcolemma and t-tubules 16 | tropomyosin slides out of position, off myosin binding sites on actin 17 I myosin quickly breaks phosphate bond of ATP 18 motor neuron action potential travels down axon, stimulating ACh release from terminals 19 :::: ::::
Transcribed Image Text:myosin heads firmly bound to actin 8. i threshold is reached and muscle action potential is generated sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 9. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasm (End of Excitation Steps) 10 11 | activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and repeat the cycle 12 | new ATP molecule binds to open ATP binding site of myosin 13 ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 | calcium binds troponin on sarcomeres of myofibril I muscle action potential travels down sarcolemma and t-tubules 16 | tropomyosin slides out of position, off myosin binding sites on actin 17 I myosin quickly breaks phosphate bond of ATP 18 motor neuron action potential travels down axon, stimulating ACh release from terminals 19 :::: ::::
! free phosphate group released from the ATP binding site of myosin very low calcium in sarcoplasm, actin and myosin unbound, troponin and tropomyosin in place I myosin heads weakly bind actin myosin heads swing forward, towards the M line of the sarcomere (i.e., power stroke) 4. ! activation of L-type voltage-gated calcium channels 9. E ADP released from the ATP binding site of myosin I myosin heads firmly bound to actin 7 I threshold is reached and muscle action potential is generated 8. sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 6. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasm (End of Excitation Steps) 10 11 activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and 12 repeat the cycle 13 ! new ATP molecule binds to open ATP binding site of myosin ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 calcium binds troponin on sarcomeres of myofibril 1. 2. 3.
Transcribed Image Text:! free phosphate group released from the ATP binding site of myosin very low calcium in sarcoplasm, actin and myosin unbound, troponin and tropomyosin in place I myosin heads weakly bind actin myosin heads swing forward, towards the M line of the sarcomere (i.e., power stroke) 4. ! activation of L-type voltage-gated calcium channels 9. E ADP released from the ATP binding site of myosin I myosin heads firmly bound to actin 7 I threshold is reached and muscle action potential is generated 8. sodium rushes into muscle fiber, causing local depolarization, and the end plate potential (type of graded potential) 6. calcium diffuses out of sarcoplasmic reticulum, raising concentration in sarcoplasm (End of Excitation Steps) 10 11 activation of calcium release channels myosin becomes re-energized and bound with ADP+P, ready to contract again and 12 repeat the cycle 13 ! new ATP molecule binds to open ATP binding site of myosin ACh diffuses across synapse and binds to ligand-gated receptors at muscle end plate 14 15 calcium binds troponin on sarcomeres of myofibril 1. 2. 3.
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