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- What genotypes, and in what frequencies, will be present in the offspring from the following matings? a. AABBaaBB b. AaBbaabb c. AaBBAABb d. AaBbAaBb9. The factors for normal hemoglobin (S) and sickle-cell hemoglobin (s) are considered codominants: heterozygous individuals have some normal red blood cells and some sickle cells but are not considered to have the disease. A heterozygote is said to have the sickle-cell trait but not the disease. A. What is the genotype of a man with the sickle-cell trait? B. If normal man marries a heterozygous woman, what do you expect for the genotypes and phenotypes of their children? C. If 2 heterozygous people marry and have 3 children who don’t have the disease, what is the chance that their fourth child will have the disease? D. Assume that medical science finds a treatment for sickle-cell anemia so that people with the disease can live out a normal life span but their genes are not changed. If 2 people are saved from the effects of the disease, marry, and have children, what would you expect for the genotypes and phenotypes of their children? Would the children…4. Define the following terms: A. genotype B. phenotype C. monohybrid D. dihybrid
- 1. What is the genotype of individual #2? Explain how you can tell 2. What is the genotype of individual #3 Explain how you can tell.1. A woman who is heterozygous for hemophilia marries a man with hemophilia. What are the genotypes and phenotypes of the children? a) What is the genotypic ratio of the above cross (Write number next to genotype)? ___________________________________________________________________ b) What is the phenotypic ratio of the above cross? (Write number next to phenotype)? ___________________________________________________________________1. The first genetic test used a short DNA sequence that was closely linked to the Huntington’s locus. The linkage distance between the DNA sequence used in the test and the actual Huntington’ disease locus was 5%. a. In a large sample of the Venezuelan family (over 2,000 individuals), what percentage of people would inherit the DNA sequence but not the Huntington’s allele (i.e. be a false positive test for Huntington’s)? b. What percentage of that large Venezuelan family would not inherit the DNA sequence but would inherit the Huntington’s allele (i.e., be a false negative test for Huntington’s)?
- 2. A woman of blood group AB marries a man of blood group A whose father was a group O. What is the probability that: a. their child will be group A? b. their child will be group B? c. one child will be group A and the other group O? d. the first child will be a girl with type AB?3. Hemophilia is a sex linked trait that does not allow for blood clotting normally. It is a recessive genetic defect. In the royal family, the mother of the Prince is a carrier for hemophilia. (XHXh) while the father is normal. ( XHY) . What is the genotype of the Prince if he carries the bleeder’s disease? What is the probability that all the female princesses are normal? Use the Punnett square to show your solution.1. The frequency of a recessive disease is 9%. What is the frequency of the allele that causes s the disease? a) What is the frequency of the dominant allele? b) What is the frequency of the carriers (heterozygotes) of the disease?
- 6. Consider that people with blue eyes must have two alleles for blue eyes since blue eye color is a recessive trait. A blue-eyed person and a brown-eyed person have an offspring with blue eyes. The brown-eyed person must A. have two alleles for blue eyes. B. have two alleles for brown eyes. C. not have the dominant brown eye allele. D, have one allele for blue eyes and one allele for brown eyes.3. A couple just had a baby, who has type-O blood. Upon learning the baby’s blood type, the father becomesinfuriated and accuses the mother of cheating on him. The mother has type-A blood and the father has type-Bblood. Knowing that the allele for type-O is recessive, answer the following questions.a. What is the relationship between the IA, IB, and i alleles?b. Is the father right? Or is he falsely accusing the mother? Explain. Include the genotypes of the parentsand the genotypes of their potential children.4. Marfan syndrome is a genetic trait caused by in a dominant allele. The trait causes a weakening of the aorta that can be fatal. A teenager whose mother has the syndrome (but whose maternal grandfather was not affected), and whose father was unaffected, is concerend that she may have the trait. a. What is the phenotype of each of her parents? Genotype? b. What is the chance that the teenager has Marfan syndrome?