A 17 years old boy who recently emigrated from India presents to emergency department with complaints of spiking fever, weight loos and lethargy. On examination he is cachectic with grey skin tone and he is found to have pronounced splenomegaly and mild hepatomegaly. Laboratory test reveal pancytopenia, especially show anemia. Microscopic examination of a bone marrow aspirate from this patient revealed parasites in the macrophages. 1. Which of the following pathogens is most likely to have caused his illness? Spirometra mansoni Echinococcs granulosus Paragonimus westermani Leishmania donovani Entamoeba histolytic 2. Which will be the important factor for pathogen differential diagnosis? Age Location of lesion Patient’s hobby Bone marrow examination Hepatosplenomegaly 3. Which methods could be used in diagnosis? Thick blood smear Stool sample Bone marrow smear Sputum sample Blood for serology 4. Which of the following factor is most likely to be involved? The pathogen migrates into bloodstream and residence in the organ The pathogen could find in liver and spleen lesion Parasites adherence to the host cell’s membrane The parasites penetrate the macrophages and proliferation The pathogen adherence to the capillary

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A 17 years old boy who recently emigrated from India presents to emergency department with complaints of spiking fever, weight loos and lethargy. On examination he is cachectic with grey skin tone and he is found to have pronounced splenomegaly and mild hepatomegaly. Laboratory test reveal pancytopenia, especially show anemia. Microscopic examination of a bone marrow aspirate from this patient revealed parasites in the macrophages.

1. Which of the following pathogens is most likely to have caused his illness?

  • Spirometra mansoni
  • Echinococcs granulosus
  • Paragonimus westermani
  • Leishmania donovani
  • Entamoeba histolytic

2. Which will be the important factor for pathogen differential diagnosis?

  • Age
  • Location of lesion
  • Patient’s hobby
  • Bone marrow examination
  • Hepatosplenomegaly

3. Which methods could be used in diagnosis?

  • Thick blood smear
  • Stool sample
  • Bone marrow smear
  • Sputum sample
  • Blood for serology

4. Which of the following factor is most likely to be involved?

  1. The pathogen migrates into bloodstream and residence in the organ
  2. The pathogen could find in liver and spleen lesion
  3. Parasites adherence to the host cell’s membrane
  4. The parasites penetrate the macrophages and proliferation
  5. The pathogen adherence to the capillary
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