A 34 week pregnant women called her obstetrician  as she was worried after coming down with a fever and sore throat.  The doctor ordered EBV testing and CMV antibody testing. EBV testing was negative, but the mother demonstrated a four fold increase in CMV IgG after a 14 day interval.

Principles Of Pharmacology Med Assist
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Chapter14: Allergy: An Overview
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A 34 week pregnant women called her obstetrician  as she was worried after coming down with a fever and sore throat.  The doctor ordered EBV testing and CMV antibody testing. EBV testing was negative, but the mother demonstrated a four fold increase in CMV IgG after a 14 day interval.

1. What is the definitive testing to be done to confirm CMV infection in the mother?


2. What are the chances her newborn will be born with symptoms of congenital CMV?


3. Why are CMV screenings on all pregnant women not a part of routine prenatal care?


4. What antibody class (IgG or IgM) would point to CMV infection in newborn testing?

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