A 45-year-old man without a history of bleeding or excessive bruising dies suddenly due to rupture of an aortic dissection. Genetic analysis at autopsy shows a defect in the gene for fibrillin. Which of the following events most likely occurs with defective fibrillin? (A) Elastic fibers in the extracellular matrix are not correctly formed (B) Hyaluronic acid in proteoglycans is not sulfated on the proper hydroxyl residues (C) Intermediate filaments are not assembled in endothelial cells (D) Shorter side chains of chondroitin sulfate are present on the proteoglycans (E) Tubulin is not polymerized correctly due to the lack of GTP in endothelial cells

A 45-year-old man without a history of bleeding or excessive bruising dies suddenly due to rupture of an aortic dissection. Genetic analysis at autopsy shows a defect in the gene for fibrillin. Which of the following events most likely occurs with defective fibrillin? (A) Elastic fibers in the extracellular matrix are not correctly formed (B) Hyaluronic acid in proteoglycans is not sulfated on the proper hydroxyl residues (C) Intermediate filaments are not assembled in endothelial cells (D) Shorter side chains of chondroitin sulfate are present on the proteoglycans (E) Tubulin is not polymerized correctly due to the lack of GTP in endothelial cells

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter22: Genes And Disease: Cancer

Section: Chapter Questions

Problem 5CT: Some desperate cancer patients consume pills or other preparations containing shark cartilage, which...

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The classic demonstration that cell plasma membranes are composed ofbilayers depends on the following kinds of data:• The membrane lipids from 4.74 x 109 erythrocytes will form a monolayerof area 0.89 m2 when spread on a water surface.• The surface of one erythrocyte is approximately 100 μm2 in area.Show that these data can be accounted for only if the erythrocyte membraneis a bilayer.
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