A 67-year-old woman complains of gradually increasing fatigue. On physical examination, she is found to be anemic and has a peripheral neuropathy characterized by loss of position and vibratory sense. Laboratory studies docu- ment a macrocytic anemia and decreased WBC and platelets counts. What pathological mechanism accounts for these findings?    Myelodysplastic sideroblastic anemia Chronic blood loss Autoantibodies against parietal cells or intrinsic factor Diabetes mellitus A diet deficient in folate

Principles Of Pharmacology Med Assist
6th Edition
ISBN:9781337512442
Author:RICE
Publisher:RICE
Chapter23: Medications Used For Cardiovascular System Disorders
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A 67-year-old woman complains of gradually increasing fatigue. On physical examination, she is found to be anemic and has a peripheral neuropathy characterized by loss of position and vibratory sense. Laboratory studies docu- ment a macrocytic anemia and decreased WBC and platelets counts. What pathological mechanism accounts for these findings?   

  • Myelodysplastic sideroblastic anemia
  • Chronic blood loss
  • Autoantibodies against parietal cells or intrinsic factor
  • Diabetes mellitus
  • A diet deficient in folate
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