A 9 year old child was brought to the clinic with a history of failure to thrive. Further examination shows generalized hypotonia and hepatomegaly. Chest X-ray images of shows massive cardiomegaly.Microscope of the muscle biopsy is shows vacuoles. Which enzyme is deficient in this disease?
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A:
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- A patient with H. pylori infection develops a gastric ulcer and is treated with omeprazole. Which of the following is/are mechanism(s) of action of omeprazole? Group of answer choices Inhibition of ACh action on parietal cells stimulation of somatostatin action on parietal cells inhibition of CCKb receptors inhibition of H+-K+ ATPase inhibition of Na+-K+ ATPase.Define the following terms:a. methotrexateb. circadian rhythmsc. calmodulind. Lesch-Nyhan syndromee. thioredoxin reductaseA 25-year-old female presented to her 28-week antenatal appointment with the complaint of lethargy, who was also noted pale Discuss the treament/managment of iron deficency anemia. Explain in detail currect and new treaments.
- Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic ketoacidosisA. Liver cirrhosisB. HypertensionC. Large abdominal herniasD. Ulcerative colitisDiabetes mellitus is characterized by insufficiency of thepancreas to produce enough insulin to regulate the blood sugarlevel. In type I diabetes, the pancreas produces no insulin, andthe patient is totally dependent on insulin from an externalsource to be infused at a rate to maintain blood sugar levelsat normal levels. Hyperglycemia occurs when blood glucoselevel rises much higher than the norm (>8 mmol/L) for pro-longed periods of time; hypoglycemia occurs when the blood sugar level falls below values of 3 mmol/L. Both situations canbe deleterious to the individual’s health. The normal range ofblood sugar is between 3.8 and 5.6 mmol/L, the target rangefor a controller regulating blood sugar.A patient with type I diabetes needs your help to maintainher blood sugar within an acceptable range (3 mmol/L<glucose<8 mmol/L). She has just eaten a large meal (a disturbance) that you estimate will release glucose accord-ing toD(t)=0.5e−0.05t,wheretis in minutes andD(t)is inmmol/L –…Which of the following caused your patient’s hyperglycemia?a. treatment for anaphylactic shock (systemic anaphylaxis)b. the presence of Glut-2 on beta cells in the pancreasc. the secretion of amylind. the presence of Glut-4 on adipose tissuee. hyponatremia
- A physician order humulin R 54 units and humulin N 40 units qam and humulin R 35 units ac evening meal subcutaneously. How many units of insulin should be injected every morning?Calcitonin has the following biological effects, except:A. Inhibition of vitamin D activityB. Decreased Ca level in bloodC. Decreased phosphorus levels in bloodD. Inhibition of gastrin secretionE. Inhibits bone resorptionMatch the following descriptions to the given choices. Enzyme involved in the conversion of arachidonic acid to leukotrienes Enzyme inhibited by non-steroidal anti-inflammatory drugs (NSAIDS) in prostaglandin synthesis Promote platelet aggregation and smooth muscle contraction Parent structure of prostaglandins A. Cyclooxygenase B. Lipoxygenase C. PGH2 D. TxB2 E. Prostanoic acid F. Arachidonic acid
- Today, due to the pandemic most people stay at home and most of them gain weight. Many weight loss products and drinks are introduced in the market which contains Carnitine: A fat mover. Explain the mechanism of action ofcarnitine in losing weight?A child was brought to the hospital was found to have hypoglycemia , hepatomegaly and accumulation of highly branched glycogen called limit dextrins .which disease is he suffering from ?Which statement is TRUE about gout? a. Gout can be treated by administration of fluorouracil. b. Gout leads to deposition of sodium urate crystals in the joints. c. Eating more liver is an effective way to treat the symptoms of gout. d. Gout is particularly prevalent in patients lacking xanthine oxidase. e. Gout is caused by excessive breakdown of pyrimidine nucleotides.