A ballerina bent her leg at an awkward angle and her tibia and fibula are obviously fractured. You palpate her posterior tibial and dorsalis pedis pulses on her non-injured limb and they are 2/4. However, on her injured limb they are 0/4.  Noticed her injury limb is becoming pale and cold to the touch distal to the touch distal to the injury. What has likely happened?

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Tissue regeneration & repair

Tissue regeneration involves the restoration of tissue components by regrowth of damaged tissues. In contrast, tissue repair involves patching of injured tissue rather than restoring it. It is the proliferative capacity of the cells that decides the amount of regeneration against the repair that would occur in the tissue. Both regeneration and repair depending on the duration of the injury and response to the inflammation.