A breeder comes to you with a female cat (Fifi) affected with a disease. This cat has an affected male sibling and 2 unaffected littermates. Their dam (mother) is normal, but Fifi’s maternal granddam is affected with the disease. Their sire (father) is normal, but Fifi’s paternal grandsire is affected. The breeder wants to mate Fifi to a normal male. This male has 2 female littermates, one that is affected with the disease and the other normal. The male’s dam is also affected with the disease but the status of the male’s sire is unknown because he is deada. Draw the pedigree using correct symbols, affected individuals and numbering the generations and individuals in the pedigree.b. What is the probability that the mating of Fifi with the described male will produce a kitten affected with the disease? 4. (6 points) A chromosome has the following segments, where represents the centromere.AB CDEFG●What typesof chromosomal mutations are required to change this chromosome into each of the followingchromosomes? BE SPECIFIC WITH YOUR ANSWER! For example, if there is an inversion, specify whichtype of inversion AND indicate which genes are affected.a. AB CDEDEFGb.A CDEFGc. C BADEFG

Name: A breeder comes to you with a female cat (Fifi) affected with a diseas
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Description: A breeder comes to you with a female cat (Fifi) affected with a disease. This cat has an affected male sibling and 2 unaffected littermates. Their dam (mother) is normal, but Fifi’s maternal granddam is affected with the disease. Their sire (father)

Introduction :- Typically, pedigrees are used to illustrate straightforward dominant and recessive…

Answered: A breeder comes to you with a female…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 3QP: A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13....

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A breeder comes to you with a female cat (Fifi) affected with a disease. This cat has an affected male sibling and 2 unaffected littermates. Their dam (mother) is normal, but Fifi’s maternal granddam is affected with the disease. Their sire (father) is normal, but Fifi’s paternal grandsire is affected. The breeder wants to mate Fifi to a normal male. This male has 2 female littermates, one that is affected with the disease and the other normal. The male’s dam is also affected with the disease but the status of the male’s sire is unknown because he is dead

a. Draw the pedigree using correct symbols, affected individuals and numbering the generations and individuals in the pedigree.

b. What is the probability that the mating of Fifi with the described male will produce a kitten affected with the disease?

4. (6 points) A chromosome has the following segments, where represents the centromere.
AB CDEFG
●
What types
of chromosomal mutations are required to change this chromosome into each of the following
chromosomes? BE SPECIFIC WITH YOUR ANSWER! For example, if there is an inversion, specify which
type of inversion AND indicate which genes are affected.
a. AB CDEDEFG
b.
A CDEFG
c. C BADEFG

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