A clinical trial is being conducted in order to determine the efficacy of a new drug used to treat Rheumatoid arthritis. The efficacy of the medication will not only be determined by the physical improvement of symptoms but also by using a blood test to examine the concentration C-reactive protein (an inflammatory marker) in an individual’s blood. If the researcher wants a margin of error for the level of C-reactive protein to be less than or equal to 3.0 mg/dL, and if the standard deviation for C-reactive protein concentrations among arthritis patients was previously documented at 8 mg/dL, how many patients should be recruited for each group in the study assuming a 95% confidence interval will be used to quantify the mean differences between the control group and the treatment group? n for the treatment group = 112; n for the control group = 111 n for the treatment group = 56; n for the control group = 57 n for the treatment group = 55; n for the control group = 55 n for the treatment group = 112; n for the control group = 112
A clinical trial is being conducted in order to determine the efficacy of a new drug used to treat Rheumatoid arthritis. The efficacy of the medication will not only be determined by the physical improvement of symptoms but also by using a blood test to examine the concentration C-reactive protein (an inflammatory marker) in an individual’s blood. If the researcher wants a margin of error for the level of C-reactive protein to be less than or equal to 3.0 mg/dL, and if the standard deviation for C-reactive protein concentrations among arthritis patients was previously documented at 8 mg/dL, how many patients should be recruited for each group in the study assuming a 95% confidence interval will be used to quantify the mean differences between the control group and the treatment group?
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It is given that both standard deviations, σ1 = σ2 = 8.
Margin of error, E = 3.0
The z-critical value for 95% confidence interval is 1.96.
Assume the sample sizes are equal for both control and treatment groups.
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