A color-blind, chromatin-positive male child (one Barr body) has a maternal grandfather who was color blind. The boy’s mother and father are phenotypically normal. Construct and support (using appropriately labeled diagrams) a rationale whereby the chromosomal and genetic attributes of the chromatin-positive male are fully explained.

A color-blind, chromatin-positive male child (one Barr body) has a maternal grandfather who was color blind. The boy’s mother and father are phenotypically normal. Construct and support (using appropriately labeled diagrams) a rationale whereby the chromosomal and genetic attributes of the chromatin-positive male are fully explained.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 1QP: The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show...

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Which of the following statements is/are true of the variegated eye color phenotype in Figure 12-23?a. The white gene is active in the white sectors and inactive in the red sectors.b. The white gene is inactive in the white sectors and active in the red sectors.c. The white gene is inactive in the white sectors due to the spread of heterochromatin.d. b and c are both true.
Indicate the expected number of Barr bodies in interphase cells of individuals with Klinefelter syndrome; Turner syndrome; and karyotypes 47,XYY, 47,XXX, and 48,XXXX.
Assume that the Holliday junctions resolve so that there is no crossing over (that is, there is no recombination). For the maternal chromosome list all of the possible base identities at the three positions after the cell repairs any mismatches. Do the same for the paternal chromosome.”
The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?
Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?
Assuming no other abnormalities, classify each of the following human sex chromosome complements as to whether or not individuals with that complement will be morphologically male or female. Three human sex chromosome complements will be classified as male and three will be classified as female. XXY XYY XXX XO XY XX
For the following chromosome complements, what is the phenotypic sex of a person who has Q. XY with the SRY gene deleted?
For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXYY with one copy of the SRY gene deleted?
Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the fact that one of the extra X Chromosome is inactivated practically leaving an XY active sex chromosomes similar to a normal male?
A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement between the second andthird chromosomes. Her chromosomes, compared to those in anormal karyotype, are diagrammed on the next page:(a) What kind of chromosomal aberration is shown?
In Figure 12-11b, in what chromosomal region are youlikely to find the most H1 histone protein?
The Xg cell-surface antigen is coded for by a gene located on the X chromosome. No equivalent gene exists on the Y chromosome. Two codominant alleles of this gene have been identified: Xg1 and Xg2. A woman of genotype Xg2/Xg2 bears children with a man of genotype Xg1/Y, and they produce a son with Klinefelter syndrome of genotype Xg1/Xg2Y. Using proper genetic terminology, briefly explain how this individual was generated. In which parent and in which meiotic division did the mistake occur?