a) draw the scheme of ETC and describe the structure of its components; b) explain how the electrochemical gradient is generated during the transport of the cleetrons; c) cxplaine what the respiratory control of the ETC and P/O ratio is.

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Chapter9: Cell Communication
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3. It is known that Leber hereditary optic neuropathy (LHON) is an inherited
form of blindness due to the missense mutations of mitochondrially encoded
proteins of complexes I or III of the ETC. Explain why disorder in the structure
of these components of ETC can impair clectron transport and oxidative
phosphorylation. For the answer:
a) draw the scheme of ETC and describe the structure of its components;
b) explain how the electrochemical gradient is generated during the transport of
the electrons;
c) explaine what the respiratory control of the ETC and P/O ratio is.
Transcribed Image Text:3. It is known that Leber hereditary optic neuropathy (LHON) is an inherited form of blindness due to the missense mutations of mitochondrially encoded proteins of complexes I or III of the ETC. Explain why disorder in the structure of these components of ETC can impair clectron transport and oxidative phosphorylation. For the answer: a) draw the scheme of ETC and describe the structure of its components; b) explain how the electrochemical gradient is generated during the transport of the electrons; c) explaine what the respiratory control of the ETC and P/O ratio is.
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