A synthetic pathway and associated diseases Dietary protein Phenylalanine (Phe) If (Phe] high Phe hydroxylase PKU Phenylpyruvic acid Albinism Cretinism Tyrosine (Tyr) Melanin Thyroxine Tyr aminotransferase Hydraxyphenylpyruvic acid (НРА) HPA oxídase Tyrosinosis Homogentisic acid (НА) HA oxidase Alkaptonuria Maleylacetoacetic acid co, + H,0 FIGURE 6-11 A section of the phenylalanine metabolic pathway in humans, including diseases associated with enzyme blockages. The disease PKU is produced when the enzyme phenylalanine hydroxylase malfunctions. Accumulation of phenylalanine results in an increase in phenylpyruvic acid, which interferes with the development of the nervous system. discovered through a standard ing response (most were steri approaches in the next section pheromone (hormone) releas» binds to a membrane receptor brane and activates the proteir sequential protein phosphoryl. cade activates the transcriptio: cell to mate. A mutation at

A synthetic pathway and associated diseases Dietary protein Phenylalanine (Phe) If (Phe] high Phe hydroxylase PKU Phenylpyruvic acid Albinism Cretinism Tyrosine (Tyr) Melanin Thyroxine Tyr aminotransferase Hydraxyphenylpyruvic acid (НРА) HPA oxídase Tyrosinosis Homogentisic acid (НА) HA oxidase Alkaptonuria Maleylacetoacetic acid co, + H,0 FIGURE 6-11 A section of the phenylalanine metabolic pathway in humans, including diseases associated with enzyme blockages. The disease PKU is produced when the enzyme phenylalanine hydroxylase malfunctions. Accumulation of phenylalanine results in an increase in phenylpyruvic acid, which interferes with the development of the nervous system. discovered through a standard ing response (most were steri approaches in the next section pheromone (hormone) releas» binds to a membrane receptor brane and activates the proteir sequential protein phosphoryl. cade activates the transcriptio: cell to mate. A mutation at

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 18P: Distinguishing the Mechanisms of Class I and Class I Aldolases Fructose bisphosphate aldolase in...

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