A few years ago researchers identified another protein involved in cell invasion by P. falciparum, Rh5.  PfRh5 is required in red blood cell invasion.  It binds to a specific protein (basigin) in red blood cell membranes and it shows almost no variation among P. falciparum strains.  What part(s) of this story is/are important relative to our discussion on malaria vaccines?  Option C: PfRh1 appears to be invariant All three of these observations (A-C) are crucial Option A: PfRh1 is required for cell invasion, i.e. no alternative pathways Option B: PfRh1 binds to basigin Options A and C

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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A few years ago researchers identified another protein involved in cell invasion by P. falciparum, Rh5.  PfRh5 is required in red blood cell invasion.  It binds to a specific protein (basigin) in red blood cell membranes and it shows almost no variation among P. falciparum strains.  What part(s) of this story is/are important relative to our discussion on malaria vaccines? 

  • Option C: PfRh1 appears to be invariant
  • All three of these observations (A-C) are crucial
  • Option A: PfRh1 is required for cell invasion, i.e. no alternative pathways
  • Option B: PfRh1 binds to basigin
  • Options A and C
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