A gene has two alleles that are associated with body mass in an additive manner. The table below shows the mean phenotype for each genotype, along with the frequency of each genotype in a population. Use this information to answer the following questions.   A1A1 A1A2 A2A2 Mean mass (kg) 50 55 60 Frequency 0.01 0.18 0.81 a)  How much does this locus contribute to additive genetic variation?   b)A second locus (B) has two alleles (B1 and B2), which are also associated with body mass in an additive manner. Each copy of the B2 allele adds 2 kg of mass. The B2 allele is at a frequency of 0.6 in the same population as the A alleles are found. How much does the B locus contribute to additive genetic variation?  c) Assume that these two loci are the only sources of additive genetic variance for body mass. The total phenotypic variance for body mass in the population is 10 kg2. What is the narrow sense heritability (h2) of body mass in this population? d)  What is the expected covariance of a child’s phenotype with the parental midpoint phenotype?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 23QP
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A gene has two alleles that are associated with body mass in an additive manner. The table below shows the mean phenotype for each genotype, along with the frequency of each genotype in a population. Use this information to answer the following questions.

 

A1A1

A1A2

A2A2

Mean mass (kg)

50

55

60

Frequency

0.01

0.18

0.81

a) 

How much does this locus contribute to additive genetic variation?

 
b)A second locus (B) has two alleles (B1 and B2), which are also associated with body mass in an additive manner. Each copy of the B2 allele adds 2 kg of mass. The B2 allele is at a frequency of 0.6 in the same population as the A alleles are found. How much does the B locus contribute to additive genetic variation? 
c) Assume that these two loci are the only sources of additive genetic variance for body mass. The total phenotypic variance for body mass in the population is 10 kg2. What is the narrow sense heritability (h2) of body mass in this population?
d) 

What is the expected covariance of a child’s phenotype with the parental midpoint phenotype?

 
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