A proportion of fentanyl is known to be lost to IV infusion bags made from PVC on storage and this effect is known to be pH dependent. Explain why you believe this effect occurs and what potentially could be done to minimise loss of fentanyl to the PVC packaging

Chemistry: Principles and Reactions
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ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:William L. Masterton, Cecile N. Hurley
Chapter22: Organic Chemistry
Section: Chapter Questions
Problem 26QAP: When aniline, C6H5NH2(Kb=7.41010) , reacts with a strong acid, its conjugate acid, C6H5NH3+, is...
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6 a)     A proportion of fentanyl is known to be lost to IV infusion bags made from PVC on storage and this effect is known to be pH dependent. Explain why you believe this effect occurs and what potentially could be done to minimise loss of fentanyl to the PVC packaging
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