A researcher studying epigenetic changes induced by exercise had participants pedal a stationary bicycle with only one leg for 45 minutes a day, 4 times a week for 3 months. They then took muscle biopsies from both legs (the one that exercised and the one that did not) and compared DNA to look for epigenetic changes induced by exercise. They found over 5,000 sites on the genome where methylation patterns differed between the DNA isolated from the exercised leg and DNA isolated from the non-exercised leg.  A. How would you predict these changes would affect transcription and translation? Is there other information you need to know to feel confident in your prediction? B. Would these changes be passed down to the participants' offspring? Why or why not? C. Why did all participants exercise only one leg rather than having two groups- one who exercised and one who did not?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question

A researcher studying epigenetic changes induced by exercise had participants pedal a stationary bicycle with only one leg for 45 minutes a day, 4 times a week for 3 months. They then took muscle biopsies from both legs (the one that exercised and the one that did not) and compared DNA to look for epigenetic changes induced by exercise. They found over 5,000 sites on the genome where methylation patterns differed between the DNA isolated from the exercised leg and DNA isolated from the non-exercised leg. 

A. How would you predict these changes would affect transcription and translation? Is there other information you need to know to feel confident in your prediction?

B. Would these changes be passed down to the participants' offspring? Why or why not?

C. Why did all participants exercise only one leg rather than having two groups- one who exercised and one who did not?

Expert Solution
steps

Step by step

Solved in 4 steps

Blurred answer
Knowledge Booster
Gene expression
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education