this question is what needs answerd the othe attached is just info for it thank you

Exercise 23.18 describes a study to determine if subjects with pre-existing cardiovasular symptoms were at an increased risk of cardiovasular events while taking sibutramine. Do the data give good reason to thinking that there is a difference between the proportions of treatment and placebo subjects wo experienced the primary outcome? (Note that sibutramine has not been available in the United States since the end of 2010 due to its' manufacturer's concerns over increased risk of heart attack or stroke, although at the present time it can still be purchased in other countries.)

a) State hypothesis, find the test statistic, and use any software for the P-value. Be sure to state the conclusion.
b) Explain simply why it is important to have a placebo group in this study?
Transcribed Image Text:daily is HAPTER 23 EXERCISES sibutramine, an appetite suppressant, were found to be profiles if they included false information in their pro- 17 Truthfulness in online profiles. Many teens have posted a social-networking website. A sample survey ate breakfast without it is gIven M and the proportion that er increased risk of cardiovascular events while taking Of 317 older teens (aged 15 to 17), 152 said y in 2007 asked a random sample of teens with online using the large sample methods of this chapter, be sure to check that idelines for their use are met and to state your conclusions in context. (a) 0.455 0.312. (b) 3.78. (c) z = 4.94. (b) 0.417 ±0.304. (a) 2.45. (c) 0.417 ±0.185. the drug. The study included 9804 overweight or obese subjects with preexisting cardiovascular disease and/or type 2 diabetes. The subjects were randomly assigned to sibutramine (4906 subjects) or a placebo (4898 subjects) in a double-blind fashion. The primary outcome mea- sured was the occurrence of any of the following events: nonfatal myocardial infarction or stroke, resuscitation after cardiac arrest, or cardiovascular death. The primary outcome was observed in 56l subjects in the sibutra- mine group and 490 subjects in the placebo group. profiles fles on a social-networking website. A sample survey clas Of 170 younger teens (aged 12 to 14), 117 said ves. Of 317 older teens (aged 15 to 17), 152 said yes, 16 6) Do these samples satisfy the guidelines for the large- sample confidence interval? (a) Find the proportion of subjects experiencing the (6) Give a 95% confidence interval for the difference between the proportions of younger and older teens who include false information in their online profiles. primary outcome for both the sibutramine and placebo groups. 18 Effects of an appetite suppressant. Subjects with pre- EXIsting cardiovascular symptoms who were receiving outramine, an appetite suppressant, were found to be at increased risk of cardiovascular events while taking (b) Can we safely use the large-sample confidence inter- val for comparing the proportions of sibutramine and placebo subjects who experienced the primary outcome? Explain.
Transcribed Image Text:ty Images CHAPTER 23 Comparing Two Proportions (c) Give a 95% confidence interval for the difference in formal ir between the proportions of sibutramine and placebo subjects who experienced the primary outcome. perform tho The sample (Optional topic) Genetically altered mice. Genetic in- completed i: tluences on cancer can be studied by manipulating the instrumento genetic makeup of mice. One of the processes that turn whereas the instruction, genes on or off (so to speak) in particular locations is called "DNA methylation." Do low levels of this process Analysis Ha dents not re nelp cause tumors? Compare mice altered to have low evels with normal mice. Of 33 mice with lowered levels 23.21 throu f DNA methylation, 23 developed tumors. None of e control group of 18 normal mice developed tumors 23.21 D n the same time period.

Name: this question is what needs answerd the othe attached is just info for
Uploaded: 2024-03-20T07:07:12.000Z
Channel: Bartleby
Description: this question is what needs answerd the othe attached is just info for it thank you Exercise 23.18 describes a study to determine if subjects with pre-existing cardiovasular symptoms were at an increased risk of cardiovasular events while taking sibu

Question

this question is what needs answerd the othe attached is just info for it thank you

Exercise 23.18 describes a study to determine if subjects with pre-existing cardiovasular symptoms were at an increased risk of cardiovasular events while taking sibutramine. Do the data give good reason to thinking that there is a difference between the proportions of treatment and placebo subjects wo experienced the primary outcome? (Note that sibutramine has not been available in the United States since the end of 2010 due to its' manufacturer's concerns over increased risk of heart attack or stroke, although at the present time it can still be purchased in other countries.)

a) State hypothesis, find the test statistic, and use any software for the P-value. Be sure to state the conclusion.
b) Explain simply why it is important to have a placebo group in this study?

daily is
HAPTER 23 EXERCISES
sibutramine, an appetite suppressant, were found to be
profiles if they included false information in their pro-
17 Truthfulness in online profiles. Many teens have posted
a social-networking website. A sample survey
ate breakfast
without it is
gIven M and the proportion that
er increased risk of cardiovascular events while taking
Of 317 older teens (aged 15 to 17), 152 said y
in 2007 asked a random sample of teens with online
using the large sample methods of this chapter, be sure to check that
idelines for their use are met and to state your conclusions in context.
(a) 0.455 0.312.
(b) 3.78.
(c) z = 4.94.
(b) 0.417 ±0.304.
(a) 2.45.
(c) 0.417 ±0.185.
the drug. The study included 9804 overweight or obese
subjects with preexisting cardiovascular disease and/or
type 2 diabetes. The subjects were randomly assigned to
sibutramine (4906 subjects) or a placebo (4898 subjects)
in a double-blind fashion. The primary outcome mea-
sured was the occurrence of any of the following events:
nonfatal myocardial infarction or stroke, resuscitation
after cardiac arrest, or cardiovascular death. The primary
outcome was observed in 56l subjects in the sibutra-
mine group and 490 subjects in the placebo group.
profiles
fles on a social-networking website. A sample survey
clas Of 170 younger teens (aged 12 to 14), 117 said ves.
Of 317 older teens (aged 15 to 17), 152 said yes, 16
6) Do these samples satisfy the guidelines for the large-
sample confidence interval?
(a) Find the proportion of subjects experiencing the
(6) Give a 95% confidence interval for the difference
between the proportions of younger and older teens
who include false information in their online profiles.
primary outcome for both the sibutramine and
placebo groups.
18 Effects of an appetite suppressant. Subjects with pre-
EXIsting cardiovascular symptoms who were receiving
outramine, an appetite suppressant, were found to be
at increased risk of cardiovascular events while taking
(b) Can we safely use the large-sample confidence inter-
val for comparing the proportions of sibutramine
and placebo subjects who experienced the primary
outcome? Explain.

ty Images
CHAPTER 23
Comparing Two Proportions
(c) Give a 95% confidence interval for the difference
in formal ir
between the proportions of sibutramine and placebo
subjects who experienced the primary outcome.
perform tho
The sample
(Optional topic) Genetically altered mice. Genetic in-
completed i:
tluences on cancer can be studied by manipulating the
instrumento
genetic makeup of mice. One of the processes that turn
whereas the
instruction,
genes on or off (so to speak) in particular locations is
called "DNA methylation." Do low levels of this process
Analysis Ha
dents not re
nelp cause tumors? Compare mice altered to have low
evels with normal mice. Of 33 mice with lowered levels
23.21 throu
f DNA methylation, 23 developed tumors. None of
e control group of 18 normal mice developed tumors
23.21 D
n
the same time period.

Accepted Answer

The researchers want to check whether the data give good reasons to thinking that there is a…

a) State hypothesis, find the test statistic, and use any software for the P-value. Be sure to state the conclusion. b) Explain simply why it is important to have a placebo group in this study?