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- Moderna and Pfizer vaccines for COVID-19 use mRNA to the Spike protein combined with lipids. Which of the following is/are advantages of this type of vaccine compared to an inactivated virus vaccine? Select ALL correct answers. a) The vaccine is more stable for transport. b) The vaccine does not contain the virus so it cannot give you COVID-19. c) The vaccine can be rapidly produced in a slightly different form to protect from variants of SARS-CoV-2. d) The vaccine does not need a booster.Which of the following are activities that a virus particle (a virion) cannot accomplish by itself? Select all that apply. a) Extract energy from food molecules b) Synthesis of capsid proteins c) Generate ATP d) Binding to a host cell e) Replication of the viral genomewe can stop the biosynthesis stage of the viral life cycle (not the stages before it) by preventing/inhibiting: A) fusion of the envelope and the plasma membrane B) replication and expression of viral nucleic acid/genome C) the virus's attachment molecules from binding to the host cell receptor D) new copies of viral nucleic acid from combining with newly made viral proteins E)budding
- In retroviruses, transcription of the provirus: A) converts viral RNA into viral DNA B) does not result in production of viral protein components C) is done by reverse transcriptase D) represents replication of viral genome/nucleic acidWhich of the following could not be used a a host cell receptor for viral entry? a.) LPS on bacterial cells b.) Surface glycoproteins on human cells c.)Flagella d.) RibosomesFind the wrong information about virus attachment and absorption to host cell. A. The surface capsid proteins of naked viruses bind to a specific cell receptor on host cell. B. For enveloped viruses, the spikes are responsible for binding to a specific cell receptor. C. A cell lacking a receptor for a specific virus is not infected by that virus. D. Animal viruses, such as HIV are highly specific and they can only infect particular cell types. E. All of these are true.
- The viral genome needs to get to the nucleus for the virus that replicates in the nucleus. In other words, the viral nucleocapsid has to overcome two barriers (i.e., plasma membrane and nuclear membrane). Compare and contrast the mechanisms by which the viruses penetrate the two membranes.Which receptor of the influenza virus is most involved in binding tothe respiratory cells?a. neuraminidase spikes b. hemagglutinin spikes c. the viral capsid d. the viral envelopeAntigenic shifts in influenza viruses are represented by dra-matic changes in the viral antigens. It is likely they arise fromrare events in which:(a) Two different influenza viruses infect a cell at the sametime(b) Two separate viruses undergo lysogenic conversion(c) Two viruses conjugate(d) Mutations accumulate(e) All of the above
- Which statement is true of viral replication? A) virus attaches to a specific receptor site on the host-cell membrane. B) Once inside the cell, the viral capsid is degraded, and the viral nucleic acid is released. C) Virus uses the host cell’s machinery to replicate and new virus particles are released. D) All of the aboveInfluenza vaccines must be changed yearly because the amino acid sequence of the viral proteins change gradually over time. Based on this information, which is the most logical conclusion? The influenza virusa) is enveloped. b) is non-enveloped.c) has a DNA genome. d) has an RNA genome.e) causes a persistent infection.To infect their specific host cells, viruses go through these chronological steps EXCEPT a. Release of progeny viruses b. Absorption and penetration of the viral particles c. Uncoating of the nucleic acid of the viral particles d. Synthesis and assembly of viral particle components