Acid-Catalyzed Nucleophilic Addition- Addition of Amines: Imine and Enamine Formation (mechanism!)1° amines add to form imines (C=NR), and 2° amines yield enamines (R₂N-C=C)CH,CH,NH2H30*+H*- H₂O- Alcohols Addition to yield hemiacetals (hemiketals), acetals (ketals) -C(OR')2 (mechanism!)H30Ⓡ+N-HCH3CH₂OH(2 equiv.)

Acid Catalysed Nucleophilic addition reactions of ketones.

Acid-Catalyzed Nucleophilic Addition - Addition of Amines: Imine and Enamine Formation (mechanism!) 1° amines add to formimines (C=NR), and 2° amines yield enamines (R₂N-C=C) H30Ⓒ H* - H₂O - Alcohols Addition to yield hemiacetals (hemiketals), acetals (ketals) -C(OR')2 (mechanism!) H30Ⓒ + CHỊCH,NH, N-H CH₂CH₂OH (2 equiv.)

Acid-Catalyzed Nucleophilic Addition - Addition of Amines: Imine and Enamine Formation (mechanism!) 1° amines add to formimines (C=NR), and 2° amines yield enamines (R₂N-C=C) H30Ⓒ H* - H₂O - Alcohols Addition to yield hemiacetals (hemiketals), acetals (ketals) -C(OR')2 (mechanism!) H30Ⓒ + CHỊCH,NH, N-H CH₂CH₂OH (2 equiv.)

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Section21.SE: Something Extra

Problem 39MP

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