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- Which of the following is not true of somatic cell gene therapy? a. White blood cells can be used. b. Somatic cells are cultured, and the desired DNA is introduced into them. c. Cells with the introduced DNA are returned to the body. d. The technique is still very experimental. e. The inserted genes are passed to the offspring.1. "What genetic material was used in this research?" 2. How does the completion of this research advance the treatment of cancer? in typed please1) What are the limitations of targeted versus whole-genome or whole-exome profiling of cancer mutations? 2) What can you infer about mutations that are common to almost all of the cells in a tumor? 3) Summarize the high-level differences between the VCF and MAF file formats. 4) How do germline and somatic mutations differ in terms of their effect on cancer risk and prognosis?
- 1. A patient has a mutated BRCA2 gene and a normal BRCA1 gene. Select the TWO answers that are correct. The patient has an increased risk of developing ovarian or breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a lesser risk of developing ovarian or breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a lesser risk of developing ovarian or breast cancer than a patient with a normal BRCA2 gene and a mutated BRCA1 gene. The patient has a greater risk of developing ovarian cancer and a lesser risk of developing breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a greater risk of developing breast cancer and a lesser risk of developing ovarian cancer than a patient with normal BRCA1 and BRCA2 genes.1. Through observing the sequence of events (A → B → C → D) found below, describe how reproductive cloning is made possible. Your response should consist of 3—5 complete sentences. SENTENCE STARTER: The process of cloning may look quite tricky, but it can actually be broken down into 4 individual steps. In step A, the cells of the organism we want to be cloned are isolated and the… 2. What is an ADVANTAGE of engaging in cloning practices similar to the one highlighted above? What reason might a farmer, livestock owner, or someone else use as justification for cloning? 3. What is a DISADVANTAGE (or potential drawback) of cloning plants, livestock, or pets?1. a. What are the three categories of genes mutated in cancer cells? What is the effect of mutation of each? b. What is the function of checkpoint controls in the cell cycle? What is checked at G1, S, G2 and M phase before the cell can progress to the next phase?
- 1) Create a graph as a better way to display the data in the table 2) Determine which mutations (5q, 18q, 17p, Ras) caused the progression to each stage of tumorigenesis.1. "What genetic material was used in this research?" 2. How does the completion of this research advance the treatment of cancer? in typed please and this is the research "The Mystery of Metastasis"3. Which of the following types of mutations would NOT be advantageous to a cancer cell? a.An inactivating mutation in pRb b.An inactivating mutation in a gene controlling a DNA damage checkpoint c.An inactivating mutation in p16INK4A d.An inactivating mutation in cyclin D e.An inactivating mutation in p19INK4D
- 7.-The decision by some high-risk women to have their breasts removed to prevent the possibility of developing cancer could be a truly life-altering decision. At first glance, this decision could make sense for those women who are at elevated risk due to genetic or family history factors. Counter that with living in a society that seems to be moving toward even greater obsession with female breasts at earlier ages (e.g., breast implants for 16th birthdays!) Learn more about oncogenes and breast cancer.: What are the benefits of learning you have a gene that may lead to cancer? What are the disadvantages of receiving such knowledge.1. Many cancers can be found early if people would participate in early detection. say your opinion to why this doesn't happen?4) Most embryonic stem cells used for research are: Answer: A) totipotent B) pluripotent C) multipotent D) all of the above