Aldehydes undergo nucleophilic addition reactions with potent nucleophiles such as water, alcohol and amino compounds. Which of the following nucleophiles will exhibit the greatest ability to attack the electrophilic carbon in the carbonyl group of ethanal? cyclohexyl alcohol para-chlorophenol isoamyl alcohol ortho-aminophenol

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter19: Enolate Anions And Enamines
Section: Chapter Questions
Problem 19.38P
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Aldehydes undergo nucleophilic addition reactions with potent nucleophiles such as water, alcohol and amino compounds. Which of the following nucleophiles will exhibit the greatest ability to attack the electrophilic carbon in the carbonyl group of ethanal?

cyclohexyl alcohol
para-chlorophenol
isoamyl alcohol
ortho-aminophenol
 
An aromatic ring should satisfy Huckel’s rule, wherein the number of electrons participating in the cyclic conjugation should be equal to 4n + 2. Which of the following cyclic structures does NOT obey Huckel’s rule?

Cyclobutadienyl dianion
Tetrahydrofuran ring
Cyclopropene structure
Pyrimidine ring structure
 
What is the role of H • ions in the nucleophilic substitution of alcohols using
hydrogen halides?
 
Removal of an alkyl group
Protonation of -OH group
Stabilization of carbocation
Activation of oxygen radical
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