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Analysis of the series of compounds below indicates that the amine (aniline) functionality is very important for binding to the 5-HT5 receptor. It is postulated that the aniline group functions as a H -bond acceptor in binding to the 5-HT5 receptor. On the basis of this information alone, arrange the compounds in order of their expected increasing affinity to the 5-HTS receptor (weakest affinity first). a. II, III, Ib. III, II, Ic. III, I, II d. I, III, II

Analysis of the series of compounds below indicates that the amine (aniline) functionality is very important for binding to the 5-HT5 receptor. It is postulated that the aniline group functions as a H -bond acceptor in binding to the 5-HT5 receptor. On the basis of this information alone, arrange the compounds in order of their expected increasing affinity to the 5-HTS receptor (weakest affinity first). a. II, III, Ib. III, II, Ic. III, I, II d. I, III, II

Chemistry: Matter and Change
Chemistry: Matter and Change
1st Edition
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Chapter8: Covalent Bonding
Section8.2: Naming Molecules
Problem 27PP
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Analysis of the series of compounds below indicates that the amine (aniline) functionality is very important for binding to the 5-HT5 receptor. It is postulated that the aniline group functions as a H -bond acceptor in binding to the 5-HT5 receptor. On the basis of this information alone, arrange the compounds in order of their expected increasing affinity to the 5-HTS receptor (weakest affinity first). a. II, III, Ib. III, II, Ic. III, I, II d. I, III, II

NH₂ F NH₂ = NH₂ F
Transcribed Image Text:NH₂ F NH₂ = NH₂ F
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