answer please?. Why does morphimne show less analge

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter19: Analgesics, Sedatives, And Hypnotics
Section: Chapter Questions
Problem 13CRQ
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Can you answer please?. 

Why does morphimne show less analgesic activity after oral administration?Explain at your own words? 

 

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