Antibiotic resistant bacteria have become a major concern for many public health officials. Widespread use of antibiotics has created an evolutionary pressure on infectious bacteria to develop immunity to these medications. The result is an increase in antibiotic resistant microbes, particularly in settings where antibiotics are commonly used, such as hospitals. One strategy public health officials have devised to counteract these infectious microbes is "antibiotic cycling” where specific antibiotics are withdrawn from the market for a period of several years, then reintroduced as another antibiotic is withdrawn.     How would this strategy help limit antibiotic resistance? A. It is impossible for a bacterium to maintain resistance to two antibiotics at once B. When a given antibiotic is not in use, it is an evolutionary disadvantage to carry the unneeded gene C. If a specific antibiotic is removed from the market it is possible to substitute with a related antibiotic such as penicillin and amoxicillin D. By removing certain antibiotics from the market, it limits the chance that the resistance genes would be involved in horizontal gene transfer

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Prokaryotic evolution

The term evolution means the gradual change or a transformation from a simple or primitive state to a complex or advanced state. Prokaryotic evolution is a concept that involves the evolution of the form and function of most primitive organisms (prokaryotes) through several stages and changes to form diverse life as a part of organic evolution.