Br NaH NH DMF several NO2 steps rizatriptan

Q: Q#7 Draw a stepwise, detailed mechanism for the following reaction. Use curved arrows to show the…

A: The above Reaction is the Nucleophilic substitution reaction . In the Reaction the Alkyl Halide…

Q: 1. Draw the four major resonance contributor of the following molecule. Show all nucleophilic atoms…

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Q: 8.45 Which of the following compounds undergoes E2 elimination with strong base? For compounds that…

A: Welcome to bartleby ! We have to tell which decalin will undergo alkene

Q: Draw the major product of the following reaction. Br OC(CH3)3

A: The detailed solution of your question given below--   Since, we know that when a bulky base is…

Q: Draw the product of the following transformations: d. CH;CH,OH H KHCO3 CH;NH2 KHCO3

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Q: Synthesizing an Ether by a Two-Step Reaction Sequence Draw the product of the following two-step…

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Q: 7.45 Draw the products of each nucleophilic substitution reaction. а. CI b. NACN с. H,0 d. ОН `CI…

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Q: 3. Draw the product to the following reactions. а. .CI AICI3 b. HNO3 H2SO4 C. Br H2SO4 heat d. NO2…

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Q: 1) H3O* 2) concentrated H2SO4, heat 3) Оз 4) DMS

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Q: Draw the product of the following Claisen reaction.

A: Claisen reaction: Intermolecular condensation reaction of esters in the presence of strong base is…

Q: Draw an alkyl halide and choose the best reaction conditions that would undergo an SN2 reaction to…

A: In organic chemistry substitution reaction are those reaction where one functional group is…

Q: Draw the reactant of the following Hofmann elimination. CH-Br 1. Ag,0. H,0 (excess) 2. heat CH,N

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Q: 8. Draw a plausible mechanism for each of the following transformations: -OH for conc. H₂SO4 heat a.…

A: Short explanation : Conc. sulfuric acid is donate its proton to alcohol and formation of…

Q: Draw the major product of the substitution reaction shown below. Ignore any inorganic byproducts. Br…

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Q: What is the product of the SN2 reaction shown below? Nat SH ? DMSO HS- HS.. SH HS b. c. d. a. Which…

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Q: li Which product(s) will be formed when CH3CHO reacts HCN? 1. CHICH2CN 2. (CH):CHOH 3. CH CH(OH)N A…

A: A chemical reaction in which alkyl halide on reaction with nucleophile forms a substituted product…

Q: 40. What is the major product of the following reaction sequence? COCH3 HCI CH3OH СООН CH3 fOCH3 CH3…

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Q: Draw the major product of the three-step synthesis shown. 1. cat. H3O* H. `Br 2. 3. H30* ZI

A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 18.2 Which of the following nitrile groups is activated toward nucleophilic attack? ENH 18.1 Draw…

A: Nucleophilic substitution reaction is one of the ost usable reaction .

Q: 1) PhMgBr 2) Hа0

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Q: 1. HBr (1 equiv) 2. HCI (1 equiv) Br A) Br B) CI Br C) D) - Br E) None of these choices. What is the…

A: Answer is explained below.

Q: What is the major product formed when the following compound undergo an E1 reaction? CH, -CH;CH;

A: Solution An chemical action may be a variety of organic reaction throughout that two substituents ar…

Q: The Robinson annulation reaction is shown below. Identify the missing reagent in the first step. КОН…

A: This reaction name is Robinson annulation reaction in which first step is Michael addition then…

Q: Draw the major product of the following three-step synthesis. 1. cat H3O* 2. Br 3. Н,о*

A: Due to the presence of acid, the lone pair of electron on N attacks on the electrophilic carbonyl…

Q: Which of the following electrophiles would undergo the slowest SN2 reaction? Br Br Br A C Which of…

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Q: r. 1. ВНз 2. H20, H2O2, NaOH S. H2 Pd/C t. HO, H2SO4

A: Hydroboration-oxidation of alkenes that means reaction of alkenes with  BH3 , H2O2-NaOH ) form less…

Q: 1) PhMgBr 2) H,0

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 24. Which of the following bases would make an E2 reaction occur at the fastest rate? ONa KCI KBr SK…

A: E2 represents for biomolecular elimination reaction.  This reaction is a one step process in which…

Q: Identify the major substitution and elimination products of the reaction below: & Br Pool of…

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Q: 6.1.3 Draw the product(s) of the following transformation.

A: Mechanism

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

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Q: H,0 Cat TSOH но OMe OMe MEOH cat. TSOH -H0

A: Ring opening reaction of epoxides goes through SN2 mechanism.

Q: Draw the product X of the following SN2 reaction. X was a key intermediate in the synthesis of…

A: Product X of the following SN2 reaction is given as,

Q: Q2/ What is the major E2 elimination product formed from each halide? CH H. CH 3. b. CH CH, CH,CH,…

A: (a) In an E2 reaction, both H and Br groups must be in anti periplanar to each other (i.e. 180…

Q: Draw the products of the following ozonolysis reactions: CH3 (1) ? + ? CH3 H,O2 CH, CH3 (2) ? + ? H.…

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Q: 10.a) In the box at the left, indicate whether the reaction takes place through an SN2, SN1, E2, or…

A: Hello. Since the question contains more than three sub-parts, the first three sub-parts shall be…

Q: "OH ? H20

A: Given,

Q: 9.47 How can you explain the observation that the SN2 reaction of (dibromomethyl)benzene with NaOH…

A: SN2 reaction: It is the chemical reaction of nucleophilic substitution in which there will be…

Q: OH H2SO4 B.

A: Protection of ketones using diols - Diols are widely used as a protecting groups for aldehyde and…

Q: Draw the product of the following reaction: 1. NaCN 2. H₂O*. A 'Br Draw the most stable enol…

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Q: Draw the expected MAJOR products of the following reactions. HBr HBr ROOR (a) (b) HBr HCL (c) (d)…

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Q: c) Draw the major product(s) for each reaction. 1. Sia,BH 2. Н,О2, NaOH Na, NH3 3-hexyne (c) xs I2…

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Q: Draw the major product of the substitution reaction shown below. Ignore any inorganic byproducts.…

A: SN1 reaction is nucleophilic substitution reaction. It is first order reaction. Rate determining…

Q: What product is formed in the Suzuki coupling of A and B? This reaction was a key step in the…

A: In Suzuki reaction, an organoboron compound is reacted with an aryl (or alkenyl) halide in the…

Q: Draw the product of the following reactions:

A: Pericyclic reactions are those reactions in which the bond-making and bond breaking takes place…

Q: H2/Pd CH30

A: Carbonyl compounds reacts with H2 in presence of catalysts Pd and undergoes reduction reaction…

Q: Br NaN3 DMF Using curved arrows, draw the mechanism for the SN2 reaction below 8:55 /

A: So we’ll draw the mechanism for above given reaction. The reaction follows SN2 pathway. As we know…

Q: 2. Draw the products for the following reaction sequences. CH-6r CH =CH2 Y.co2 Br NaOMe HBr Mg ROOR…

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Q: CH3 HCI

A: A double bond is protonated by an acid to produce the most stable carbocation as the major…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.