Asked Oct 9, 2019

Briefly describe and compare sinusoids and fenestrated capillaries with continuous capillaries. Give one specific organ where you would find these types of capillaries and describe their role in the organs in which they are present.


-Fenestrated capillaries:

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Step 1

Capillaries are small (3 to 4 µm) blood vessels that connect venules to the arterioles. Capillaries permit the exchange of wastes and nutrients between the blood and tissues of the body. Capillaries are categorized into three main types: fenestrated capillaries, continuous capillaries, and discontinuous capillaries.

Step 2

Sinusoids are larger than capillaries, mainly found in organs like bone marrow, spleen, liver, and adrenal glands. They have a large area between the endothelial cells because the basal lamina is either absent or discontinuous. Thus, sinusoids are more permeable to nutrient exchange.

In the liver, sinusoids receive blood from distal branches of the portal vein and hepatic artery and bring it into the central veins. Hepatic sinusoids also act as a phagocytic system of the body. Sinusoids have an abundant population of Kupffer cells, it is a type of macrophage that engulf extra debris in the blood.

Step 3

Fenestrated capillaries are found in tissues that have more exchange of nutrients with the blood like small intestine, kidney, and endocrine glands. They have larger pores that allow the exchange of molecules. The fenestrated capillaries are more permeable than continuous capillaries. The glomerulus of the kidney has an abundant network of fenestrated capillaries. These capillaries help in purification of blood during urine formation.

Continuous capillaries are those capillaries that have a continuous lining of endothelial cell...

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