C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 m) Length ( 10 0 20 m) 15 Length ( 10 5 0 20 a 40 40 60 80 60 Time (seconds) 80 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?

C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 m) Length ( 10 0 20 m) 15 Length ( 10 5 0 20 a 40 40 60 80 60 Time (seconds) 80 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter37: The Endocrine System

Section: Chapter Questions

Problem 1VCQ: Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In...

See similar textbooks

Similar questions

make note on tubulin inhibitors and role of taxols as mitotic inhibitors. please answer in two part first about microtubulin inhabitors and then role of taxols as mitotic inhabitors on detail plz
GIVE GRAPHICAL MODEL BASED ON GIVEN INFORMATION: There are three elements in this specific model: Alpha Secretase: This node represents the variable or concept of Alpha Secretase, a proteolytic enzyme that cleaves Beta-Amyloid molecules. Beta-Amyloid Formation: This node represents the variable or concept of Beta-Amyloid Formation, which describes the process of the formation and accumulation of Beta-Amyloid protein in the brain. It is regarded as toxic and contributes to the onset of Alzheimer's disease. Calcium signaling: This node represents the variable or concept of Calcium Signaling, which refers to the cellular process involving the regulation and influx of calcium ions. Alzheimer's disease is known to influence calcium signaling pathways. The directed edges in the graph indicate the causal relationships between the variables. The situation: There is a directed edge between Alpha Secretase and Beta-Amyloid Formation, indicating that Alpha Secretase has a direct…
Discuss/explain, in details, the relationship between cell viability and cell vitality and cell apoptosis as suggested by neutral red uptake,
Which of the following changes to the microtubule binding protein, Tau, commonly occurs in Alzheimerâ s and other neurodegenerative diseases? A Tau is hypo-phosphorylated and does not bind to microtubules to destabilize them. B Tau levels are so low in the cell that they only bind to some microtubules. C Tau is hyper-phosphorylated and does not bind to microtubules to stabilize them. D Microtubules are hyper-phosphorylated and do not bind to Tau.
Explain about the below: Cancer Cells Contain Genetic Defects Affecting ChromatinModifications
You have found a plant-derived compound that interferes with microtubule assembly by binding to and blocking free cytosolic tubulin. This compound might help treat ____________ by preventing microtubule ___________. Select one: a. Parkinsons, retraction b. Parkinsons, extension c. Cancer, retraction d. Cancer, extension e. Cancer, organizing center formation
Briefly describe why a cell would need a family of chaperone proteins called “heat shock proteins” (HSPs). What is the role of HSPs in the cell? How do HSPs recognize their target? (5 sentence max) Please answer asap and in short
Please select a disease (like cancer) that can be modeled through the generation of induced pluripotent stem cells. And explain it. And please give information and explain the modeling of this disease with IPS cells. provide information about the process
Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?
What is the status of tissue engineering and stem cell reseaech in the Philippines. In not more than 2 two paragraphs, DESCRIBE THE STATUS OF TISSUE ENGINEERING AND STEM CELL THERAPHY IN THE PHILIPPINES.
What is the status of tissue engineering and stem cell reseaech in the Philippines. DESCRIBE THE STATUS OF TISSUE ENGINEERING AND STEM CELL THERAPHY IN THE PHILIPPINES.
Describe and explain the picture below: with cancer treatment the stages of treatment and what happens to the normal cells compared to tumor cells