C3Why is C3 tested on all complement components? What are the three complement pathways used by the body? How is each activated? What are processes involved in each pathway that leads to cell lysis?

INTRODUCTION The cell is the basic structural and functional unit of life forms. Every cell…

Answered: C3 tested on all complement components?

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C3 tested on all complement components?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter42: The Immune System

Section: Chapter Questions

Problem 23CTQ: If a series of genetic mutations prevented some, blit not all, of the complement proteins from...

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Why is C3 tested on all complement components?
What are the three complement pathways used by the body? How is each activated?
What are processes involved in each pathway that leads to cell lysis?

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C3 Why is C3 tested on all complement components? What are the three complement pathways used by the body? How is each activated? What are processes involved in each pathway that leads to cell lysis?
True/False: The classical and lectin pathways of complement activation converge at the step of C3 activation. However, the initiating steps of each pathway use protein components and enzymatic mechanisms that share no similarity with each other.
True or False: FHL patients show increased susceptibility to infection because secretion of IFN-γ in cytotoxic granules is impaired. True or False: Autoimmune-like symptoms of patients with complement deficiencies are due to the complement pathway’s normal functions in clearing immune complexes from the circulation.
Two BMI2607 students are studying for the May/June exam, when they reach a learning unit on the body’s defensive systems. One of them insists that complement is part of the nonspecific second line of defense, but the partner insists that complement is part of an antibody immune response in the third line of defense. As the third person to join them, discuss how would you explain to them that they are both correct?
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20) A 19 -year old man comes to the physician because of a severely itchy, blistering rash on his legs for 2 days. The rash began 1 dayafter he went for a walk in a wooded area and has increased in size since then. Physical exmaintaion shows erythematous plaques with vesicles and bullae over both lower extremities. Which of the following is the most likely caise of the patients condition? (A) Activation of the alternative complement pathway (B) Chemical burn caused by toxic plant resins (C) Deposition of immune complexes in the epidermis (D) Infiltrtion of the skin by lymphocytes and macrophages (E) Local discharge of histamine in response to IgE cross lnking of allergen.
True/False: The C3 convertase of the alternative complement pathway amplifies the overall magnitude of complement activation regardless of which of the three pathways initiated the complement activation initially.
Which one of these does not pertain to Complement Select one: A. Is a series of proteins present in the plasma. B. Is a specific defense mechanism. C. Plays a role in destroying bacteria. D. Is involved in the inflammatory response.
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