Cardiac output cannot increase indefinitely because (a) available filling time becomes shorter as the heart rate increases. (b) the cardiac center adjusts the heart rate. (c) the rate of spontaneous depolarization decreases. (d) the ion concentrations surrounding pacemaker plasma membranes decrease.

Human Physiology: From Cells to Systems (MindTap Course List)
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ISBN:9781285866932
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Chapter10: The Blood Vessels And Blood Pressure
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Cardiac output cannot increase indefinitely because
(a) available filling time becomes shorter as the heart rate
increases.
(b) the cardiac center adjusts the heart rate.
(c) the rate of spontaneous depolarization decreases.
(d) the ion concentrations surrounding pacemaker plasma
membranes decrease.

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