CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?
CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?
Chapter12: 1+1=3 (or More)
Section: Chapter Questions
Problem 1.2CS
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