CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?

An Illustrated Guide To Vet Med Term
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CASESTUDY 11 .1
Immediately following the birth of a baby girl, the attending physician
requested a protein electrophoretic examination of the mother's serum. This
was done on a sample that was obtained on the mother's admission to the
hospital the previous day. An electrophoretic examination was also
performed on the cord blood specimen. Laboratory reports are shown in
Case Study Table 11.1.1.
The appearance of the mother's electrophoretic pattern was within that
expected for a healthy person. The electrophoretic pattern of the cord blood
serum resembled the one shown in Figure 11.8C.
Results for
Maternal
Serum
Results
for Cord
Blood
Adult
Reference
Interval
Test
Albumin
4.2 g/dL
3.5 g/dL
3.5-5.0 g/dL
a,-Globulins
0.3 g/dL
0.0 g/dL
0.1-0.4 g/dL
a-Globulins
1.2 g/dL
0.4 g/dL
0.3-0.8 g/dL
B-Globulins
1.3 g/dL
0.7 g/dL
0.6-1.1 g/dL
Y-Globulins
1.3 g/dL
1.0 g/dL
0.5-1.7 g/dL
Questions
1. What protein fraction is abnormal in the cord blood serum?
2.
An abnormality in this fraction is most often associated with what
disease?
3. What other test(s) may be done to confirm this abnormality?
Transcribed Image Text:CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL Y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?
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