Cathy is pregnant for the second time. Her first child, Donald, has cystic fibrosis. Cathy has two brothers Charles and Colin, and a sister, Cindy. Colin and Cindy are unmarried. Charles is married to an unrelated woman, Carolyn, and has a 2-year old daughter, Debbie. Cathy's parents are Bob and Betty. Betty's sister Barbara is the mother of Cathy's husband, Calvin, who is 25. There is no previous family history of CF. Assume that everyone in this family is of Northern European Origin. A. Sketch the pedigree, using standard symbols. B. What is the pattern of transmission of CF, and what is the risk for CF for Cathy's next child? C. Which people in this pedigree are compound heterozygotes?
Cathy is pregnant for the second time. Her first child, Donald, has cystic fibrosis. Cathy has two brothers Charles and Colin, and a sister, Cindy. Colin and Cindy are unmarried. Charles is married to an unrelated woman, Carolyn, and has a 2-year old daughter, Debbie. Cathy's parents are Bob and Betty. Betty's sister Barbara is the mother of Cathy's husband, Calvin, who is 25. There is no previous family history of CF. Assume that everyone in this family is of Northern European Origin. A. Sketch the pedigree, using standard symbols. B. What is the pattern of transmission of CF, and what is the risk for CF for Cathy's next child? C. Which people in this pedigree are compound heterozygotes?
Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter17: Development And Aging
Section: Chapter Questions
Problem 3CT: One of your best friends tells you that she and her husband think she might be pregnant. She feels...
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Transcribed Image Text:Cathy is pregnant for the second time. Her first child, Donald, has cystic fibrosis. Cathy has two
brothers Charles and Colin, and a sister, Cindy. Colin and Cindy are unmarried. Charles is married to an
unrelated woman, Carolyn, and has a 2-year old daughter, Debbie. Cathy's parents are Bob and Betty.
Betty's sister Barbara is the mother of Cathy's husband, Calvin, who is 25. There is no previous family
history of CF. Assume that everyone in this family is of Northern European Origin.
A. Sketch the pedigree, using standard symbols.
B. What is the pattern of transmission of CF, and what is the risk for CF for Cathy's next child?
C. Which people in this pedigree are compound heterozygotes?
D. What is the chance of Charles having a child with cystic fibrosis? Show your work.
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Cathy is pregnant for the second time. Her first child, Donald, has cystic fibrosis. Cathy has two brothers Charles and Colin, and a sister, Cindy. Colin and Cindy are unmarried. Charles is married to an unrelated woman, Carolyn, and has a 2-year old daughter, Debbie. Cathy's parents are Bob and Betty. Betty's sister Barbara is the mother of Cathy's husband, Calvin, who is 25. There is no previous family history of CF. Assume that everyone in this family is of Northern European Origin.
D. What is the chance of Charles having a child with cystic fibrosis? Show your work.
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