Cell were equally distributed into two culture dishes containing bovine serum. One culture dish was treated with antibodies to integrins that block their ability to bind to extracellular proteins in the extracellular space, and one dish was treated with control antibodies that have no blocking ability. The cells were allowed to attach and then assayed for their ability to migrate. What do you predict will be the result of this experiment? There would be no effect of the blocking antibody. Cells in both plates would attach and migrate equally well. Cells in both plates would be unable to either attach or migrate. The cells with the blocking antibody would not be able to attach to the plate and would not migrate, but the cells with the control antibody would adhere and migrate. The cells with the control antibody would not be able to attach to the plate and would not migrate, but the cells with the blocking antibody would adhere and migrate.
Cell were equally distributed into two culture dishes containing bovine serum. One culture dish was treated with antibodies to integrins that block their ability to bind to extracellular proteins in the extracellular space, and one dish was treated with control antibodies that have no blocking ability. The cells were allowed to attach and then assayed for their ability to migrate. What do you predict will be the result of this experiment?
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There would be no effect of the blocking antibody. Cells in both plates would attach and migrate equally well. |
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Cells in both plates would be unable to either attach or migrate. |
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The cells with the blocking antibody would not be able to attach to the plate and would not migrate, but the cells with the control antibody would adhere and migrate. |
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The cells with the control antibody would not be able to attach to the plate and would not migrate, but the cells with the blocking antibody would adhere and migrate. |
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