Organic And Biological Chemistry
7th Edition
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:STOKER, H. Stephen (howard Stephen)
Chapter3: Alcohols, Phenols And Ethers
Section: Chapter Questions
Problem 3.79EP
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Organomagnesium compounds
The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.
Hydrolysis Grignard Reactions and Reduction
Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.
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Aprepitant (trade name Emend) is used to prevent the acute nausea and vomiting caused by chemotherapy. Identify E and F, intermediates in the synthesis of aprepitant.
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