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Please provide the solution to the attached question for part c :)
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- 1. Williamson Ether Synthesis Questions for lab , Synthesize phenacetin from acetaminophen (Tylenol) via a Williamson ether synthesis. a.Find the missing reagent:CH3CH2OH +? → C2H5OC2H5 H2SO4, H2O HNO3, H2CO3 b.What is the nucleophile in this reaction? H2O Nu- RO- ROH c.If you wanted to prepare Guaifenesin (present in OTC cough meds), choose the alcohol you would start with? 2 methoxy benzoinc acid 2-methoxy benzaldehyde 2-methoxyphenol 2 methoxy anisole d.What was the mechanism of the reaction you used to prepare the ether? SN1 SN2 E1 E2 e.The reaction given below is known as by which o the following reaction? C2H5ONa+IC2H5→C2H5OC2H5+NaI Oxidation reaction Williamson reduction reaction Williamson ether synthesis Wittig synthesis f.Chloroethane reacts with X to form diethyl ether. What is X?…Which reagents would you use to perform reaction B?a) PBr3.b) p-toluenesulfonyl chloride.c) SOCl2.d) NaOCl, NaOHPlease answer in detail and show all your work, thank you! Synthesis of Ibuprofen-Part 2: Some pain relievers including ibuprofen (Motrin ® and naproxen (Aleve B are " α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
- select the most appropriate reagent(s) to effect the change. K2Cr2O7, H+ H2, Pd 1. Disiamylborane, 2. HO–, H2O, H2O2 NaOCl H2SO4, HgSO4based on this video: on Hinsberg Test Tests for Amines - MeitY OLabs (8.5min) https://www.youtube.com/watch?v=j5jgMUWri8U Write the reaction (two-step, in skeletal) of each test amine when tested in the Hinsberg Test.What is the best set of reagents to use for the synthesis?
- 1.Explain why pyridine ( Kb=2.3x10-9) is a much stronger base than pyrrole (Kb=2.5x10-14), 2.Explain and illustrate, why it is difficult to perfom Friedel-Craft reactions on unactivated pyridine.show how you might prepare 1-penten-3-one from 3-pentanoneChemistry Draw the product formed when phenylacetaldehyde (C6H5CH2CHO) is treated with reach reagent: f. (CH3)2CHNH2, mild acid g. (CH3CH2)2NH, mild acid h. CH3CH2OH (excess), H+ i. piperidine, mild acid j. HOCH2CH2OH, H+