CHM 2 125 LABORATORY MANUAL Chemistry 2125: Organic Laboratory I Chemistry of Amines I. Purpose of the Experiment: II. Reactions Carried Out: a. aniline with tosyl chloride b. N-methylaniline with tosyl chloride c. aniline with nitrous acid followed by reaction with B-naphthol III. An unknown amine reacts with tosyl chloride in basic media to generate a cle a strong acid, a precipitate forms. This same amine undergoes reaction with so acid at cold temperature, and upon warming, a colorless gas is evolved. What inf these experiments?

CHM 2 125 LABORATORY MANUAL Chemistry 2125: Organic Laboratory I Chemistry of Amines I. Purpose of the Experiment: II. Reactions Carried Out: a. aniline with tosyl chloride b. N-methylaniline with tosyl chloride c. aniline with nitrous acid followed by reaction with B-naphthol III. An unknown amine reacts with tosyl chloride in basic media to generate a cle a strong acid, a precipitate forms. This same amine undergoes reaction with so acid at cold temperature, and upon warming, a colorless gas is evolved. What inf these experiments?

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.59P

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Account for the following :(i) Primary amines (R-NH2) have higher boiling point than tertiary amines (R3N).(ii) Aniline does not undergo Friedel – Crafts reaction.(iii) (CH3)2NH is more basic than (CH3)3N in an aqueous solution.
The shrub ma huang (Section 5.4A) contains two biologically activestereoisomers—ephedrine and pseudoephedrine—with two stereogeniccenters as shown in the given structure. Ephedrine is one component ofa once-popular combination drug used by body builders to increaseenergy and alertness, whereas pseudoephedrine is a nasaldecongestant.a.) Draw the structure of naturally occurring (−)-ephedrine, which has the1R,2S configuration.b.) Draw the structure of naturally occurring (+)-pseudoephedrine, whichhas the 1S,2S configuration.c.) How are ephedrine and pseudoephedrine related?d.) Draw all other stereoisomers of (−)-ephedrine and (+) pseudoephedrine, and give the R,S designation for all stereogeniccenters.e.) How is each compound drawn in part (d) related to (−)-ephedrine?
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